In the past decade, mesenchymal stem cells (MSCs) tend to exhibit inherent tropism for
refractory inflammatory diseases and engineered MSCs have appeared on the market as …

Peripheral nerve injuries (PNIs) are common and debilitating, cause significant health care
costs for society, and rely predominately on autografts, which necessitate grafting a nerve …

Increasing studies show that inflammatory processes may be involved in depressive
disorders. Nuclear factor erythroid-2 related factor 2 (Nrf2) modulates tissue microglial M1 …

Despite the advances in the regeneration/rehabilitation field of damaged tissues, the
functional recovery of peripheral nerves (PNs), especially in a long gap injury, is considered …

Bioactive macromolecular drugs known as Growth Factors (GFs), approved by the Food and
Drug Administration (FDA), have found successful application in clinical practice. They hold …

Background The autologous nerve graft, despite its donor site morbidity and unpredictable
functional recovery, continues to be the gold standard in peripheral nerve repair. Rodent …

Alzheimer's disease (AD) is a very common neurodegenerative disorder associated with
memory loss and a progressive decline in cognitive activity. The two major …

Adipose‐derived mesenchymal stem cells (ASCs) may transdifferentiate into cells belonging
to mesodermal, endodermal, and ectodermal lineages. The aim of this study was to verify …

Objectives To evaluate the rapid repair potential of adipose‐derived stem cells (ADSCs) co‐
overexpressing VEGF and GDNF on bilateral cavernous nerve injury (BCNI) in rat models …

Schwann cells (SCs) play a central role in peripheral nervous system physiology and in the
response to axon injury. The ability of SCs to proliferate, secrete growth factors, modulate …