Cellular microenvironments are generally sophisticated, but crucial for regulating the
functions of human pluripotent stem cells (hPSCs). Despite tremendous effort in this field, the …

Mesenchymal stem cells and pluripotent stem cells are recognized as promising tools for
tissue engineering, cell therapy, and drug screening. Their use in therapy requires the …

The efficient genesis of pluripotent cells or therapeutic cells for regenerative medicine
involves several external manipulations and conditioning protocols, which drives down …

Despite the fact that porcine embryonic stem cells (ESCs) are a practical study tool, in vitro
long-term maintenance of these cells is difficult in a two-dimensional (2D) microenvironment …

Cell therapy is a promising approach for the treatment of patients suffering from myocardial
infarction. Most recent therapies involve direct injection of cells into the damaged heart …

Cells accomplish the process of fate decisions and form terminal lineages through a series
of binary choices in which cells switch stable states from one branch to another as the …

Human embryonic stem cells (hESCs) are characterized by both their pluripotency and
ability to self-renew, rendering them attractive for treatment of degenerative diseases. The …

With the rapid development of stem cell-related therapies and regenerative medicine, the
clinical application of stem cell products is on the rise. However, ensuring the effectiveness …

Design is essential to engineering. ABET requires that engineering graduates must
demonstrate “an ability to apply engineering design to produce solutions that meet specified …

In vitro modeling of hematological malignancies not only provides insights into the influence
of genetic aberrations on cellular and molecular mechanisms involved in disease …