Recent trends in therapeutic strategies for repairing endometrial tissue in intrauterine adhesion

J Ma, H Zhan, W Li, L Zhang, F Yun, R Wu, J Lin… - Biomaterials …, 2021 - Springer
Intrauterine adhesion (IUA) is a common gynaecological disease that develops from
infection or trauma. IUA disease may seriously affect the physical and mental health of …

Aging conundrum: A perspective for ovarian aging

J Wu, Y Liu, Y Song, L Wang, J Ai, K Li - Frontiers in Endocrinology, 2022 - frontiersin.org
Progressive loss of physiological integrity and accumulation of degenerative changes
leading to functional impairment and increased susceptibility to diseases are the main …

Growth hormone reduces aneuploidy and improves oocytes quality by JAK2-MAPK3/1 pathway in aged mice

YY Luo, X Zeng, L Zhu, C Li, J Xie, Q Dong… - Journal of Translational …, 2023 - Springer
Background The global delay in women's reproductive age has raised concerns about age-
related infertility. The decline in oocyte quality is a limiting factor of female fertility, yet there …

Administration of growth hormone improves endometrial function in women undergoing in vitro fertilization: a systematic review and meta-analysis

Y Shang, M Wu, R He, Y Ye… - Human Reproduction …, 2022 - academic.oup.com
BACKGROUND The positive effects of growth hormone (GH) on IVF are often attributed to
improvements in oocyte and embryo quality. While emerging evidence emphasizes GH …

Growth hormone protects against ovarian granulosa cell apoptosis: Alleviation oxidative stress and enhancement mitochondrial function

J Wang, J Wu, Y Zhang, J Zhang, W Xu, C Wu… - Reproductive …, 2021 - Elsevier
Growth hormone (GH) is a polypeptide hormone that could reduce the mitochondria-
mediated oxidative stress and improve the mitochondrial function. However, the …

The clinical application of growth hormone and its biological and molecular mechanisms in assisted reproduction

P Pan, X Huang - International Journal Of Molecular Sciences, 2022 - mdpi.com
Growth hormone (GH) has been used as a co-gonadotrophin in assisted reproduction,
particularly in poor ovarian responders. The application of GH has been alleged to activate …

[HTML][HTML] Growth hormone ameliorates the age-associated depletion of ovarian reserve and decline of oocyte quality via inhibiting the activation of Fos and Jun …

C Liu, S Li, Y Li, J Tian, X Sun, T Song, G Yan… - Aging (Albany …, 2021 - ncbi.nlm.nih.gov
Oocyte quality typically begins to decline with aging, which contributes to subfertility and
infertility. However, there is still no effective treatment to restore the ovarian reserve and …

The effect of growth hormone on the metabolome of follicular fluid in patients with diminished ovarian reserve

F He, F Wang, Y Yang, Z Yuan, C Sun, H Zou… - Reproductive Biology …, 2023 - Springer
Background Increasing evidence supports that the co-treatment with growth hormone (GH)
enhances ovarian response and oocyte quality during controlled ovarian stimulation (COS) …

Towards personalized antioxidant use in female infertility: Need for more molecular and clinical studies

J Tesarik - Biomedicines, 2021 - mdpi.com
Treatment with antioxidants is increasingly used to slow down aging processes in different
organs of the human body, including those implicated in female fertility. There is a plethora …

Importance of IGF-I levels in IVF: potential relevance for growth hormone (GH) supplementation

N Gleicher, SK Darmon, E Molinari, P Patrizio… - Journal of assisted …, 2022 - Springer
Purpose Growth hormone (GH) supplementation in association with in vitro fertilization (IVF)
is worldwide again increasing, even though study outcomes have been discrepant. Since …