Background Drug resistance monitoring of the paediatric HIV-1-infected population is
required to optimize treatment success and preserve future treatment options. Objectives To …

In resourced settings with access to highly active antiretroviral therapy, perinatally acquired
HIV-1 infection has become a chronic disease of childhood with increasing numbers of …

Nucleoside/nucleotide reverse transcriptase inhibitors (NRTIs) are essential components in
first-line therapy for human immunodeficiency virus (HIV) infection. However, long-term …

We sought to determine the pattern of resistance-associated mutations (RAMs) among HIV-1-
infected children failing first-line antiretroviral therapy (ART) and ascertain their response to …

Background: Without virologic testing, HIV-infected African children starting antiretroviral
(ARV) therapy are at risk for undetected virologic failure and the development of ARV …

Background We studied prevalence of etravirine (ETR) and rilpivirine (RPV) resistance in
HIV-1 subtype CRF01_AE infection with first-line non-nucleoside reverse transcriptase …

Efavirenz is a non-nucleoside reverse transcriptase inhibitor (NNRTI), used for the treatment
of human immunodeficiency virus (HIV)-1 infection. Approved by the US Food and Drug …

Objective: To analyze the genotypic resistance profiles of HIV-infected children from rural
China who were experiencing virologic failure to first-line antiretroviral therapy regimens …

Objectives To assess long-term virological efficacy and the emergence of drug resistance in
children who receive antiretroviral treatment (ART) in rural Tanzania. Patients and methods …

In 2004, Malawi began scaling up its national antiretroviral therapy (ART) program. Because
of limited treatment options, population-level surveillance of acquired human …