Metabolomics and lipidomics in NAFLD: biomarkers and non-invasive diagnostic tests
Nonalcoholic fatty liver disease (NAFLD) is one of the most common liver diseases
worldwide and is often associated with aspects of metabolic syndrome. Despite its …
worldwide and is often associated with aspects of metabolic syndrome. Despite its …
[HTML][HTML] Metabolic-associated fatty liver disease and lipoprotein metabolism
J Heeren, L Scheja - Molecular metabolism, 2021 - Elsevier
Background Non-alcoholic fatty liver disease, or as recently proposed 'metabolic-associated
fatty liver disease'(MAFLD), is characterized by pathological accumulation of triglycerides …
fatty liver disease'(MAFLD), is characterized by pathological accumulation of triglycerides …
Saroglitazar, a PPAR‐α/γ agonist, for treatment of NAFLD: a randomized controlled double‐blind phase 2 trial
S Gawrieh, M Noureddin, N Loo, R Mohseni… - …, 2021 - Wiley Online Library
Background and Aims NAFLD is characterized by insulin resistance and dysregulated lipid
and glucose metabolism. Saroglitazar, a dual peroxisome proliferator activated receptor‐α/γ …
and glucose metabolism. Saroglitazar, a dual peroxisome proliferator activated receptor‐α/γ …
Non-alcoholic fatty liver disease and risk of incident diabetes mellitus: an updated meta-analysis of 501 022 adult individuals
A Mantovani, G Petracca, G Beatrice, H Tilg, CD Byrne… - Gut, 2021 - gut.bmj.com
Objective Follow-up studies have shown that non-alcoholic fatty liver disease (NAFLD) is
associated with an increased risk of incident diabetes, but currently, it is uncertain whether …
associated with an increased risk of incident diabetes, but currently, it is uncertain whether …
[HTML][HTML] Role of insulin resistance in MAFLD
Y Sakurai, N Kubota, T Yamauchi… - International journal of …, 2021 - mdpi.com
Many studies have reported that metabolic dysfunction is closely involved in the complex
mechanism underlying the development of non-alcoholic fatty liver disease (NAFLD), which …
mechanism underlying the development of non-alcoholic fatty liver disease (NAFLD), which …
[HTML][HTML] Adipose tissue dysfunction as determinant of obesity-associated metabolic complications
Obesity is a critical risk factor for the development of type 2 diabetes (T2D), and its
prevalence is rising worldwide. White adipose tissue (WAT) has a crucial role in regulating …
prevalence is rising worldwide. White adipose tissue (WAT) has a crucial role in regulating …
[HTML][HTML] Myosteatosis in the context of skeletal muscle function deficit: an interdisciplinary workshop at the National Institute on Aging
R Correa-de-Araujo, O Addison, I Miljkovic… - Frontiers in …, 2020 - frontiersin.org
Skeletal muscle fat infiltration (known as myosteatosis) is an ectopic fat depot that increases
with aging and is recognized to negatively correlate with muscle mass, strength, and mobility …
with aging and is recognized to negatively correlate with muscle mass, strength, and mobility …
[HTML][HTML] Mechanisms of insulin action and insulin resistance
MC Petersen, GI Shulman - Physiological reviews, 2018 - journals.physiology.org
The 1921 discovery of insulin was a Big Bang from which a vast and expanding universe of
research into insulin action and resistance has issued. In the intervening century, some …
research into insulin action and resistance has issued. In the intervening century, some …
[HTML][HTML] Sphingolipids in metabolic disease: The good, the bad, and the unknown
The bioactive sphingolipid metabolites ceramide and sphingosine-1-phosphate (S1P) are a
recent addition to the lipids accumulated in obesity and have emerged as important …
recent addition to the lipids accumulated in obesity and have emerged as important …
Non-alcoholic fatty liver disease: causes, diagnosis, cardiometabolic consequences, and treatment strategies
The prevalence of non-alcoholic fatty liver disease (NAFLD) is increasing worldwide. In
some patients with NAFLD, isolated steatosis can progress to advanced stages with non …
some patients with NAFLD, isolated steatosis can progress to advanced stages with non …