Nonalcoholic fatty liver disease (NAFLD) is one of the most common liver diseases
worldwide and is often associated with aspects of metabolic syndrome. Despite its …

Background Non-alcoholic fatty liver disease, or as recently proposed 'metabolic-associated
fatty liver disease'(MAFLD), is characterized by pathological accumulation of triglycerides …

Background and Aims NAFLD is characterized by insulin resistance and dysregulated lipid
and glucose metabolism. Saroglitazar, a dual peroxisome proliferator activated receptor‐α/γ …

Objective Follow-up studies have shown that non-alcoholic fatty liver disease (NAFLD) is
associated with an increased risk of incident diabetes, but currently, it is uncertain whether …

Many studies have reported that metabolic dysfunction is closely involved in the complex
mechanism underlying the development of non-alcoholic fatty liver disease (NAFLD), which …

Obesity is a critical risk factor for the development of type 2 diabetes (T2D), and its
prevalence is rising worldwide. White adipose tissue (WAT) has a crucial role in regulating …

Skeletal muscle fat infiltration (known as myosteatosis) is an ectopic fat depot that increases
with aging and is recognized to negatively correlate with muscle mass, strength, and mobility …

The 1921 discovery of insulin was a Big Bang from which a vast and expanding universe of
research into insulin action and resistance has issued. In the intervening century, some …

The bioactive sphingolipid metabolites ceramide and sphingosine-1-phosphate (S1P) are a
recent addition to the lipids accumulated in obesity and have emerged as important …

The prevalence of non-alcoholic fatty liver disease (NAFLD) is increasing worldwide. In
some patients with NAFLD, isolated steatosis can progress to advanced stages with non …