Gene regulation in a cellular environment is a stochastic phenomenon leading to a large
variability in mRNAs and protein numbers that are often produced in bursts. The regulation …

Expression of a gene is inherently random, leading to variability in a protein's level across a
population of cells with same genetic information and environment. Another consequence of …

Many biological systems exhibit precise timing of events, and one of the most known
examples is cell lysis, which is a process of breaking bacterial host cells in the virus infection …

The timing of diverse cellular processes is based on the instant when the concentration of
regulatory proteins crosses a critical threshold level. Hence, noise mechanisms inherent to …

Phosphorelays are signal transduction circuits that sense environmental changes and adjust
cellular metabolism. Five different circuit architectures account for 99% of all phosphorelay …

Failure in maintaining protein solubility in vivo impairs protein homeostasis and results in
protein misfolding and aggregation, which are often associated with severe …

Bacterial gene expression regulation occurs mostly during transcription, which has two main
rate-limiting steps: the close complex formation, when the RNA polymerase binds to an …

We investigate the influence of large noise on the formation of localized patterns in the
framework of the cubic-quintic complex Ginzburg-Landau equation. The interaction of …

This paper explores the possibility of building a structured corporate knowledge base that
documents the results of the search for valuable information as well as its own …

An important step in execution of several cellular processes is accumulation of a regulatory
protein up to a specific threshold level. Since production of a protein is inherently stochastic …