Genetic determinants of arterial thrombosis

B Voetsch, J Loscalzo - Arteriosclerosis, thrombosis, and vascular …, 2004 - Am Heart Assoc
Arterial thrombosis is a complex disorder that involves multiple genetic and environmental
factors interacting to produce the characteristic phenotype. In the past decades, investigators …

[图书][B] Hemostasis and thrombosis: basic principles and clinical practice

VJ Marder, WC Aird, JS Bennett, S Schulman… - 2012 - books.google.com
Since publication of the First Edition in 1982, Hemostasis and Thrombosis has established
itself as the pre-eminent book in the field of coagulation disorders. No other book is as …

How to Use SNP_TATA_Comparator to Find a Significant Change in Gene Expression Caused by the Regulatory SNP of This Gene's Promoter via a Change in …

M Ponomarenko, D Rasskazov… - BioMed Research …, 2015 - Wiley Online Library
The use of biomedical SNP markers of diseases can improve effectiveness of treatment.
Genotyping of patients with subsequent searching for SNPs more frequent than in norm is …

[HTML][HTML] Obesity-related known and candidate SNP markers can significantly change affinity of TATA-binding protein for human gene promoters

OV Arkova, MP Ponomarenko, DA Rasskazov… - BMC genomics, 2015 - Springer
Background Obesity affects quality of life and life expectancy and is associated with
cardiovascular disorders, cancer, diabetes, reproductive disorders in women, prostate …

[HTML][HTML] Pharmacogenetic and clinical risk factors for bevacizumab-related gastrointestinal hemorrhage in prostate cancer patients treated on CALGB 90401 (Alliance)

JN Patel, C Jiang, K Owzar, DL Hertz, J Wang… - The …, 2024 - nature.com
The objective of this study was to discover clinical and pharmacogenetic factors associated
with bevacizumab-related gastrointestinal hemorrhage in Cancer and Leukemia Group B …

[HTML][HTML] Candidate SNP markers of familial and sporadic Alzheimer's diseases are predicted by a significant change in the affinity of TATA-binding protein for human …

P Ponomarenko, I Chadaeva, DA Rasskazov… - Frontiers in Aging …, 2017 - frontiersin.org
While year after year, conditions, quality, and duration of human lives have been improving
due to the progress in science, technology, education, and medicine, only eight diseases …

[HTML][HTML] Candidate SNP markers of reproductive potential are predicted by a significant change in the affinity of TATA-binding protein for human gene promoters

IV Chadaeva, PM Ponomarenko, DA Rasskazov… - BMC genomics, 2018 - Springer
Background The progress of medicine, science, technology, education, and culture
improves, year by year, quality of life and life expectancy of the populace. The modern …

Candidate SNP Markers of Chronopathologies Are Predicted by a Significant Change in the Affinity of TATA‐Binding Protein for Human Gene Promoters

P Ponomarenko, D Rasskazov, V Suslov… - BioMed Research …, 2016 - Wiley Online Library
Variations in human genome (eg, single nucleotide polymorphisms, SNPs) may be
associated with hereditary diseases, their complications, comorbidities, and drug responses …

[HTML][HTML] Bioinformatics applications in life sciences and technologies

SA Sousa, JH Leitão, RC Martins… - BioMed research …, 2016 - ncbi.nlm.nih.gov
Life sciences researchers collect and analyse a high amount of different types of scientific
data, including DNA, RNA, and amino acid sequences, in situ and microarray gene …

Prediction of the affinity of the TATA-binding protein to TATA boxes with single nucleotide polymorphisms

PM Ponomarenko, MP Ponomarenko, IA Drachkova… - Molecular Biology, 2009 - Springer
The TATA-binding protein (TBP) is the subunit of basal transcription factor TFIID that
recognizes the TATA boxes of TATA-containing promoters in class II genes, binds to them …