Adiponectin is one of the most important adipocytokines secreted by adipocytes and is
called a “guardian angel adipocytokine” owing to its unique biological functions. Adiponectin …

Skeletal muscle and adipose tissue are the two largest organs in the body. Skeletal muscle
is an effector organ, and adipose tissue is an organ that stores energy; in addition, they are …

In 2015, EFSA established a temporary tolerable daily intake (t‐TDI) for BPA of 4 μg/kg body
weight (bw) per day. In 2016, the European Commission mandated EFSA to re‐evaluate the …

Adipose tissue is a critical regulator of systemic metabolism and normal bodily homeostasis.
Recently, the immune system has been implicated in the regulation of adipose tissue …

During the last decades, research on adipose tissues has spread in parallel with the
extension of obesity. Several observations converged on the idea that adipose tissues are …

Brown fat is a specialized fat depot that can increase energy expenditure and produce heat.
After the recent discovery of the presence of active brown fat in human adults and novel …

The ever-increasing incidence of obesity and related disorders impose serious challenges
on public health worldwide. Brown adipose tissue (BAT) has strong capacity for promoting …

Distinct oxygenases and their oxylipin products have been shown to participate in
thermogenesis by mediating physiological adaptations required to sustain body …

Hepatic lipogenesis is aberrantly induced in nonalcoholic fatty liver disease (NAFLD) via
activation of the LXR-SREBP1c pathway. To date, a number of protein factors impinging on …

Excess adiposity can induce adverse sequelae in multiple cell types and organ systems.
The transition from the lean to the obese state is characterized by fundamental cellular …