DNA origami

S Dey, C Fan, KV Gothelf, J Li, C Lin, L Liu… - Nature Reviews …, 2021 - nature.com
Biological materials are self-assembled with near-atomic precision in living cells, whereas
synthetic 3D structures generally lack such precision and controllability. Recently, DNA …

Functionalizing DNA origami to investigate and interact with biological systems

GA Knappe, EC Wamhoff, M Bathe - Nature Reviews Materials, 2023 - nature.com
DNA origami has emerged as a powerful method to generate DNA nanostructures with
dynamic properties and nanoscale control. These nanostructures enable complex …

[HTML][HTML] Creating complex protocells and prototissues using simple DNA building blocks

N Arulkumaran, M Singer, S Howorka… - Nature …, 2023 - nature.com
Building synthetic protocells and prototissues hinges on the formation of biomimetic skeletal
frameworks. Recreating the complexity of cytoskeletal and exoskeletal fibers, with their …

Protein‐mimicking nanoparticles in biosystems

X Ji, Q Li, H Song, C Fan - Advanced Materials, 2022 - Wiley Online Library
Proteins are essential elements for almost all life activities. The emergence of
nanotechnology offers innovative strategies to create a diversity of nanoparticles (NPs) with …

Advancing biophysics using DNA origami

W Engelen, H Dietz - Annual review of biophysics, 2021 - annualreviews.org
DNA origami enables the bottom-up construction of chemically addressable, nanoscale
objects with user-defined shapes and tailored functionalities. As such, not only can DNA …

[HTML][HTML] Responsive core-shell DNA particles trigger lipid-membrane disruption and bacteria entrapment

M Walczak, RA Brady, L Mancini, C Contini… - Nature …, 2021 - nature.com
Biology has evolved a variety of agents capable of permeabilizing and disrupting lipid
membranes, from amyloid aggregates, to antimicrobial peptides, to venom compounds …

[HTML][HTML] Fabricating higher-order functional DNA origami structures to reveal biological processes at multiple scales

Y Zhou, J Dong, Q Wang - NPG Asia Materials, 2023 - nature.com
DNA origami technology enables the precise assembly of well-defined two-dimensional and
three-dimensional nanostructures with DNA, an inherently biocompatible material. Given …

[HTML][HTML] Reversible membrane deformations by straight DNA origami filaments

HG Franquelim, H Dietz, P Schwille - Soft Matter, 2021 - pubs.rsc.org
Membrane-active cytoskeletal elements, such as FtsZ, septin or actin, form filamentous
polymers able to induce and stabilize curvature on cellular membranes. In order to emulate …

Recent advances of DNA nanostructure‐based cell membrane engineering

L Feng, J Li, J Sun, L Wang, C Fan… - Advanced Healthcare …, 2021 - Wiley Online Library
Materials that can regulate the composition and structure of the cell membrane to fabricate
engineered cells with defined functions are in high demand. Compared with other …

Coating and stabilization of liposomes by clathrin-inspired DNA self-assembly

KN Baumann, L Piantanida, J García-Nafría, D Sobota… - Acs Nano, 2020 - ACS Publications
The self-assembly of the protein clathrin on biological membranes facilitates essential
processes of endocytosis and has provided a source of inspiration for materials design by …