DNA origami
Biological materials are self-assembled with near-atomic precision in living cells, whereas
synthetic 3D structures generally lack such precision and controllability. Recently, DNA …
synthetic 3D structures generally lack such precision and controllability. Recently, DNA …
Functionalizing DNA origami to investigate and interact with biological systems
DNA origami has emerged as a powerful method to generate DNA nanostructures with
dynamic properties and nanoscale control. These nanostructures enable complex …
dynamic properties and nanoscale control. These nanostructures enable complex …
[HTML][HTML] Creating complex protocells and prototissues using simple DNA building blocks
Building synthetic protocells and prototissues hinges on the formation of biomimetic skeletal
frameworks. Recreating the complexity of cytoskeletal and exoskeletal fibers, with their …
frameworks. Recreating the complexity of cytoskeletal and exoskeletal fibers, with their …
Protein‐mimicking nanoparticles in biosystems
Proteins are essential elements for almost all life activities. The emergence of
nanotechnology offers innovative strategies to create a diversity of nanoparticles (NPs) with …
nanotechnology offers innovative strategies to create a diversity of nanoparticles (NPs) with …
Advancing biophysics using DNA origami
DNA origami enables the bottom-up construction of chemically addressable, nanoscale
objects with user-defined shapes and tailored functionalities. As such, not only can DNA …
objects with user-defined shapes and tailored functionalities. As such, not only can DNA …
[HTML][HTML] Responsive core-shell DNA particles trigger lipid-membrane disruption and bacteria entrapment
Biology has evolved a variety of agents capable of permeabilizing and disrupting lipid
membranes, from amyloid aggregates, to antimicrobial peptides, to venom compounds …
membranes, from amyloid aggregates, to antimicrobial peptides, to venom compounds …
[HTML][HTML] Fabricating higher-order functional DNA origami structures to reveal biological processes at multiple scales
DNA origami technology enables the precise assembly of well-defined two-dimensional and
three-dimensional nanostructures with DNA, an inherently biocompatible material. Given …
three-dimensional nanostructures with DNA, an inherently biocompatible material. Given …
[HTML][HTML] Reversible membrane deformations by straight DNA origami filaments
Membrane-active cytoskeletal elements, such as FtsZ, septin or actin, form filamentous
polymers able to induce and stabilize curvature on cellular membranes. In order to emulate …
polymers able to induce and stabilize curvature on cellular membranes. In order to emulate …
Recent advances of DNA nanostructure‐based cell membrane engineering
Materials that can regulate the composition and structure of the cell membrane to fabricate
engineered cells with defined functions are in high demand. Compared with other …
engineered cells with defined functions are in high demand. Compared with other …
Coating and stabilization of liposomes by clathrin-inspired DNA self-assembly
The self-assembly of the protein clathrin on biological membranes facilitates essential
processes of endocytosis and has provided a source of inspiration for materials design by …
processes of endocytosis and has provided a source of inspiration for materials design by …