COVID-19 pandemics Stage II–energy and environmental impacts of vaccination

JJ Klemeš, P Jiang, Y Van Fan, A Bokhari… - … and Sustainable Energy …, 2021 - Elsevier
The COVID-19 pandemic developed the severest public health event in recent history. The
first stage for defence has already been documented. This paper moves forward to …

In vitro-in vivo correlation in nanocarriers: From protein corona to therapeutic implications

TG Agnihotri, A Alexander, M Agrawal… - Journal of Controlled …, 2023 - Elsevier
Understanding and establishing a link between the physicochemical characteristics of
nanoparticles (NPs) and their biological interactions poses to be a great challenge in the …

Introduction to pharmaceutical product development

R Shukla, M Handa, VP Pardhi - Pharmaceutical drug product …, 2020 - taylorfrancis.com
The development of a new pharmaceutical product is the need of time to address the rising
pressure on pharmaceutical industries for introducing new clinical candidates in the drug …

[HTML][HTML] Preformulation studies: a versatile tool in formulation design

K Ahirwar, R Shukla - Drug Formulation Design, 2023 - intechopen.com
The physicochemical properties of pharmacological molecules have a tremendous effect on
safety and efficacy. Poor physicochemical properties can often make it hard to set up a …

In vitro profiling of fenofibrate solid dispersion mediated tablet formulation to treat high blood cholesterol

U Atneriya, D Kapoor, J Sainy, R Maheshwari - Annales pharmaceutiques …, 2023 - Elsevier
Objective Fenofibrate (FNF), an anti-hyperlipidemic agent, suffers from poor water solubility
(0.000707 mg/ml) and belongs to class II drug as per BCS, shows a slow dissolution rate …

Prodrug design for improving the biopharmaceutical properties of therapeutic drugs

D Choudhary, H Goykar, D Kalyane… - The Future of …, 2020 - Elsevier
The prodrug concept is a very useful approach for the optimization of ADMET (absorption,
distribution, metabolism, excretion, and toxicity) properties of pharmacologically active …

Computer-aided drug discovery of c-Abl kinase inhibitors from plant compounds against chronic myeloid leukemia

MM Alshehri, N Kumar, NA Kuthi, Z Olaide… - Journal of …, 2024 - Taylor & Francis
Chronic myeloid leukemia (CML) is a hematological malignancy characterized by the
neoplastic transformation of hematopoietic stem cells, driven by the Philadelphia (Ph) …

Hydrotropy, mixed hydrotropy, and mixed solvency as trending concept for solubilization of lipophilic drugs

A Padiyar, OP Agrawal, K Rajpoot… - The Future of …, 2020 - Elsevier
The term “hydrotropy” is generally used to enhance the solubility of the drug agents by
mixing a sufficient amount of alkali metal salts. Nevertheless, this term describes nonmicelle …

Development of bedaquiline nanoemulsions intended for paediatric multidrug-resistant tuberculosis: excipient selection and preformulation studies

TO Ajayi, MS Poka, BA Witika - Frontiers in Medical Technology, 2024 - frontiersin.org
Preformulation investigations into the development of drug formulations, encompassing
considerations related to the structure of the drug, excipients, composition, and physical …

[HTML][HTML] IVIVC assessment, pharmacokinetic evaluation, and X-ray radiography mapping of Novel Parteck® SRP 80 and hypromellose-loaded LTD4 receptor …

S Jawed, CS Satish - Future Journal of Pharmaceutical Sciences, 2023 - Springer
Background The current research aims to determine the pharmacokinetic parameters,
mucoadhesive strength, and IVIVC correlation of the novel chronotherapeutic drug delivery …