[HTML][HTML] Traumatic brain injury in women across lifespan

MO Blaya, AP Raval, HM Bramlett - Neurobiology of disease, 2022 - Elsevier
Traumatic brain injury (TBI) is a leading cause of death and disability and a global public
health challenge. Every year more than 50 million people suffer a TBI, and it is estimated …

Systematic review of sex and gender effects in traumatic brain injury: equity in clinical and functional outcomes

T Mollayeva, S Mollayeva, N Pacheco… - Frontiers in …, 2021 - frontiersin.org
Background: Although traumatic brain injury (TBI) is a leading cause of death and disability
in male and female patients worldwide, little is known about the effect of sex and gender on …

Timing matters: Sex differences in inflammatory and behavioral outcomes following repetitive blast mild traumatic brain injury

BM Baskin, AF Logsdon, SJ Lee, BD Foresi… - Brain, behavior, and …, 2023 - Elsevier
Background Repetitive blast-related mild traumatic brain injury (mTBI) caused by exposure
to high explosives is increasingly common among warfighters as well as civilians. While …

[HTML][HTML] Lipocalin-2 is a key regulator of neuroinflammation in secondary traumatic and ischemic brain injury

JH Kim, RJ Kang, SJ Hyeon, H Ryu, H Joo, Y Bu… - …, 2023 - Elsevier
Reactive glial cells are hallmarks of brain injury. However, whether these cells contribute to
secondary inflammatory pathology and neurological deficits remains poorly understood …

Sex differences in behavioral symptoms and the levels of circulating GFAP, tau, and NfL in patients with traumatic brain injury

D Sass, VA Guedes, EG Smith, R Vorn… - Frontiers in …, 2021 - frontiersin.org
Traumatic brain injury (TBI) affects millions of Americans each year and has been shown to
disproportionately impact those subject to greater disparities in health. Female sex is one …

Moderate and severe TBI in children and adolescents: the effects of age, sex, and injury severity on patient outcome 6 months after injury

L Kennedy, M Nuno, GG Gurkoff, K Nosova… - Frontiers in …, 2022 - frontiersin.org
The interaction of age, sex, and outcomes of children with head injury remains incompletely
understood and these factors need rigorous evaluation in prognostic models for pediatric …

[HTML][HTML] Sex specific effects of buprenorphine on behavior, astrocytic opioid receptor expression and neuroinflammation after pediatric traumatic brain injury in mice

Y Hamood, M Abdullah, H El Ghoul, N Saad… - Brain, Behavior, & …, 2022 - Elsevier
Children who suffered traumatic brain injury (TBI) often experience acute and chronic pain,
which is linked to a poor quality of life. Buprenorphine (BPN) is commonly used to treat …

Long-Term Functional Outcome and Quality of Life in Long-Term Traumatic Brain Injury Survivors

W Taalas, R Raj, J Öhman, J Siironen - Neurotrauma Reports, 2023 - liebertpub.com
Early functional outcome assessments of traumatic brain injury (TBI) survivors may
underestimate the long-term consequences of TBI. We assessed long-term temporal …

The features of the typical traumatic brain injury patient in the ICU are changing: what will this mean for the intensivist?

VFJ Newcombe, A Chow - Current opinion in critical care, 2021 - journals.lww.com
This review highlights the urgent need to develop more age-inclusive TBI consensus
management guidelines aimed at improving short-and long-term outcomes for the large and …

Repeat subconcussion in the adult rat gives rise to behavioral deficits similar to a single concussion but different depending upon sex

RJ Wilson, MR Bell, KR Giordano, S Seyburn… - Behavioural Brain …, 2023 - Elsevier
Although concussions are a popular focus of neurotrauma research, subconcussions occur
with higher frequency but are less well-studied. A subconcussion is an impact to the head …