Developments in factor Xa inhibitors for the treatment of thromboembolic disorders
YK Lee, MR Player - Medicinal Research Reviews, 2011 - Wiley Online Library
Thromboembolic diseases are the leading causes of morbidity and mortality in the
developed world. Anticoagulants provide effective treatment for venous or arterial …
developed world. Anticoagulants provide effective treatment for venous or arterial …
Discovery of R-142086 as a factor Xa (fXa) inhibitor: Syntheses and structure–activity relationships of cinnamyl derivatives
T Noguchi, N Tanaka, T Nishimata, R Goto… - Chemical and …, 2009 - jstage.jst.go.jp
To develop a novel and effective anticoagulant with potent and selective factor Xa (FXa)
inhibitory activity, a new series of cinnamyl derivatives with enhanced lipophilicity and …
inhibitory activity, a new series of cinnamyl derivatives with enhanced lipophilicity and …
Advances in inhibitors of FXa
L Guo, S Ma - Current Drug Targets, 2015 - ingentaconnect.com
Thromboembolic diseases such as deep vein thrombosis (DVT), pulmonary embolism (PE),
myocardial infarction (MI) and ischemic strokes are mainly responsible for people's morbidity …
myocardial infarction (MI) and ischemic strokes are mainly responsible for people's morbidity …