Beyond Descartes and Newton: Recovering life and humanity

SA Kauffman, A Gare - Progress in biophysics and molecular biology, 2015 - Elsevier
Attempts to 'naturalize'phenomenology challenge both traditional phenomenology and
traditional approaches to cognitive science. They challenge Edmund Husserl's rejection of …

Biomimetic selenocystine based dynamic combinatorial chemistry for thiol-disulfide exchange

A Canal-Martín, R Pérez-Fernández - Nature Communications, 2021 - nature.com
Dynamic combinatorial chemistry applied to biological environments requires the exchange
chemistry of choice to take place under physiological conditions. Thiol-disulfide exchange …

Enzyme-based NAND and NOR logic gates with modular design

J Zhou, MA Arugula, J Halamek, M Pita… - The Journal of Physical …, 2009 - ACS Publications
The logic gates NAND/NOR were mimicked by enzyme biocatalyzed reactions activated by
sucrose, maltose and phosphate. The subunits performing AND/OR Boolean logic …

Bottom‐Up Construction of an Adaptive Enzymatic Reaction Network

B Helwig, B van Sluijs, AA Pogodaev… - Angewandte …, 2018 - Wiley Online Library
The reproduction of emergent behaviors in nature using reaction networks is an important
objective in synthetic biology and systems chemistry. Herein, the first experimental …

Fuel‐selective transient activation of nanosystems for signal generation

F Della Sala, S Maiti, A Bonanni, P Scrimin… - Angewandte …, 2018 - Wiley Online Library
The transient activation of function using chemical fuels is common in nature, but much less
in synthetic systems. Progress towards the development of systems with a complexity similar …

Kinetic self-sorting of dynamic covalent catalysts with systemic feedback regulation

F Schaufelberger, O Ramstrom - Journal of the American …, 2016 - ACS Publications
Constructing small molecule systems that mimic the functionality exhibited in biological
reaction networks is a key objective of systems chemistry. Herein, we report the …

Multi-enzyme logic network architectures for assessing injuries: digital processing of biomarkers

J Halamek, V Bocharova, S Chinnapareddy… - Molecular …, 2010 - pubs.rsc.org
A multi-enzyme biocatalytic cascade processing simultaneously five biomarkers
characteristic of traumatic brain injury (TBI) and soft tissue injury (STI) was developed. The …

Amplification of enantiomeric excess, mirror-image symmetry breaking and kinetic proofreading in Soai reaction models with different oligomeric orders

JC Micheau, C Coudret, JM Cruz… - Physical Chemistry …, 2012 - pubs.rsc.org
A comprehensive kinetic analysis of three prototypical autocatalytic cycle models based on
the absolute asymmetric Soai reaction is presented. The three models, which can give rise …

Molecular computing: paths to chemical Turing machines

S Varghese, JAAW Elemans, AE Rowan… - Chemical science, 2015 - pubs.rsc.org
To comply with the rapidly increasing demand of information storage and processing, new
strategies for computing are needed. The idea of molecular computing, where basic …

A bistable switch in dynamic thiodepsipeptide folding and template‐directed ligation

R Mukherjee, R Cohen‐Luria, N Wagner… - Angewandte Chemie …, 2015 - Wiley Online Library
Bistable reaction networks provide living cells with chemically controlled mechanisms for
long‐term memory storage. Such networks are also often switchable and can be flipped from …