Cisplatin is a widely used chemotherapeutic agent used to treat solid tumours, such as
ovarian, head and neck, and testicular germ cell. A known complication of cisplatin …

The kidney consists of numerous cell types organized into the nephron, which is the basic
functional unit of the kidney. Any stimuli that induce loss of these cells can induce kidney …

Background Current management of AKI, a potentially fatal disorder that can also initiate or
exacerbate CKD, is merely supportive. Therefore, deeper understanding of the molecular …

Renal fibrosis is considered as the pathway of almost all kinds of chronic kidney diseases
(CKD) to the end stage of renal diseases (ESRD). Ganoderic acid (GA) is a group of …

Genome-wide association studies (GWAS) have identified loci for kidney disease, but the
causal variants, genes, and pathways remain unknown. Here we identify two kidney disease …

Acute kidney injury (AKI) is a fatal medical episode caused by sudden kidney damage or
failure, leading to the death of patients within a few hours or days. Previous studies …

The kidneys are a vital organ that is vulnerable to both acute kidney injury (AKI) and chronic
kidney disease (CKD) which can be caused by numerous risk factors such as ischemia …

Optimal tissue oxygenation is essential for its normal function. Suboptimal oxygenation or
ischemia contributes to increased mortalities during various pathological conditions such as …

Background and aims: Diabetic kidney is more sensitive to ischemia/reperfusion (I/R) injury,
which is associated with increased oxidative stress and impaired nuclear factor erythroid 2 …

BACKGROUND: Bisphenol A (BPA) is a ubiquitous environmental toxin that accumulates in
chronic kidney disease (CKD). Our aim was to explore the effect of chronic exposition of BPA …