Lipid nanoparticles for nasal/intranasal drug delivery
S Cunha, MH Amaral, JMS Lobo… - Critical Reviews™ in …, 2017 - dl.begellhouse.com
Studies on the development of drug delivery systems have increased because these
systems have particular characteristics that allow them to improve therapeutics. Among …
systems have particular characteristics that allow them to improve therapeutics. Among …
[HTML][HTML] The search for novel analgesics: targets and mechanisms
TL Yaksh, SA Woller, R Ramachandran… - F1000prime …, 2015 - ncbi.nlm.nih.gov
The management of the pain state is of great therapeutic relevance to virtually every medical
specialty. Failure to manage its expression has deleterious consequence to the well-being …
specialty. Failure to manage its expression has deleterious consequence to the well-being …
Double optimization of rivastigmine-loaded nanostructured lipid carriers (NLC) for nose-to-brain delivery using the quality by design (QbD) approach: formulation …
Rivastigmine is a drug commonly used in the management of Alzheimer's disease that
shows bioavailability problems. To overcome this, the use of nanosystems, such as …
shows bioavailability problems. To overcome this, the use of nanosystems, such as …
In situ mucoadhesive-thermosensitive liposomal gel as a novel vehicle for nasal extended delivery of opiorphin
Previous studies proved the effectiveness of an intravenous PEGylated liposomal
formulation of opiorphin (1 mg/mL) in protecting the drug from enzymatic degradation, and …
formulation of opiorphin (1 mg/mL) in protecting the drug from enzymatic degradation, and …
[图书][B] Therapeutic peptides and proteins: formulation, processing, and delivery systems
AK Banga - 2005 - taylorfrancis.com
Upon publication of the first edition of Therapeutic Peptides and Proteins ten years ago there
were only 19 biotechology medicines on the market. Currently there are more than 100, with …
were only 19 biotechology medicines on the market. Currently there are more than 100, with …
In silico approaches for predicting the half-life of natural and modified peptides in blood
This paper describes a web server developed for designing therapeutic peptides with
desired half-life in blood. In this study, we used 163 natural and 98 modified peptides whose …
desired half-life in blood. In this study, we used 163 natural and 98 modified peptides whose …
Quality by design (QbD) optimization of diazepam-loaded nanostructured lipid carriers (NLC) for nose-to-brain delivery: Toxicological effect of surface charge on …
Diazepam is commonly used in the management of epileptic seizures, although it has
limitations that can be overcome by using formulations that are easier to administer and …
limitations that can be overcome by using formulations that are easier to administer and …
Protein and peptide biopharmaceuticals: an overview
Bioactive proteins and peptides are recognised as novel therapeutic molecules with varying
biological properties for potential medical applications. Development of protein and …
biological properties for potential medical applications. Development of protein and …
PACAP as a neuroprotective factor in ischemic neuronal injuries
S Shioda, T Nakamachi - Peptides, 2015 - Elsevier
Pituitary adenylate cyclase-activating polypeptide (PACAP) is a 27-or 38-amino acid
neuropeptide, which belongs to the vasoactive intestinal polypeptide/glucagon/secretin …
neuropeptide, which belongs to the vasoactive intestinal polypeptide/glucagon/secretin …
In situ gel-forming system: an attractive alternative for nasal drug delivery
X Wang, G Liu, J Ma, S Guo, L Gao… - Critical Reviews™ in …, 2013 - dl.begellhouse.com
Intranasal delivery is one of the most interesting and challenging endeavors facing
pharmaceutical scientists. The conventional nasal drug delivery systems including solutions …
pharmaceutical scientists. The conventional nasal drug delivery systems including solutions …