Therapeutic effects of green tea polyphenol (‒)-Epigallocatechin-3-Gallate (EGCG) in relation to molecular pathways controlling inflammation, oxidative stress, and …

D Mokra, M Joskova, J Mokry - International journal of molecular sciences, 2022 - mdpi.com
(‒)-Epigallocatechin-3-gallate (EGCG) is the most abundant polyphenol in green tea.
Thanks to multiple interactions with cell surface receptors, intracellular signaling pathways …

Progress in the mechanism and targeted drug therapy for COPD

C Wang, J Zhou, J Wang, S Li, A Fukunaga… - … and Targeted Therapy, 2020 - nature.com
Chronic obstructive pulmonary disease (COPD) is emphysema and/or chronic bronchitis
characterised by long-term breathing problems and poor airflow. The prevalence of COPD …

[HTML][HTML] Herbs as an antioxidant arsenal for periodontal diseases

A Ramesh, SS Varghese, JN Doraiswamy… - Journal of …, 2016 - ncbi.nlm.nih.gov
Herbal medicines have long been used as a traditional mode of therapy for various ailments
in India. They are being used increasingly as dietary supplements to ward off common …

New perspectives for mucolytic, anti-inflammatory and adjunctive therapy with 1, 8-cineole in COPD and asthma: review on the new therapeutic approach

LJ Juergens, H Worth, UR Juergens - Advances in therapy, 2020 - Springer
Abstract The mucolytic monoterpene 1, 8-cineole (eucalyptol), the major constituent of
eucalyptus species, is well known for its anti-inflammatory, antioxidant, bronchodilatory …

COPD immunopathology

G Caramori, P Casolari, A Barczyk, AL Durham… - Seminars in …, 2016 - Springer
The immunopathology of chronic obstructive pulmonary disease (COPD) is based on the
innate and adaptive inflammatory immune responses to the chronic inhalation of cigarette …

Mechanisms, pathophysiology and currently proposed treatments of chronic obstructive pulmonary disease

SO Rodrigues, CMC Cunha, GMV Soares, PL Silva… - Pharmaceuticals, 2021 - mdpi.com
Chronic obstructive pulmonary disease (COPD) is one of the leading global causes of
morbidity and mortality. A hallmark of COPD is progressive airflow obstruction primarily …

Lung inflammation caused by inhaled toxicants: a review

J Wong, BE Magun, LJ Wood - International journal of chronic …, 2016 - Taylor & Francis
Exposure of the lungs to airborne toxicants from different sources in the environment may
lead to acute and chronic pulmonary or even systemic inflammation. Cigarette smoke is the …

Mitochondrial dysfunction in chronic respiratory diseases: implications for the pathogenesis and potential therapeutics

W Zhou, J Qu, S Xie, Y Sun… - Oxidative Medicine and …, 2021 - Wiley Online Library
Mitochondria are indispensable for energy metabolism and cell signaling. Mitochondrial
homeostasis is sustained with stabilization of mitochondrial membrane potential, balance of …

The role of FUNDC1 in mitophagy, mitochondrial dynamics and human diseases

H Liu, C Zang, F Yuan, C Ju, M Shang, J Ning… - Biochemical …, 2022 - Elsevier
Mitochondria are the principal sites of energy metabolism and provide most of the energy
needed for normal cellular function. They are dynamic organelles that constantly undergo …

Machine-learning algorithm-based prediction of diagnostic gene biomarkers related to immune infiltration in patients with chronic obstructive pulmonary disease

Y Zhang, R Xia, M Lv, Z Li, L Jin, X Chen… - Frontiers in …, 2022 - frontiersin.org
Objective This study aims to identify clinically relevant diagnostic biomarkers in chronic
obstructive pulmonary disease (COPD) while exploring how immune cell infiltration …