Inflammatory and oxidative biomarkers as determinants of functional capacity in patients with COPD assessed by 6-min walk test-derived outcomes

CDC Neves, VKS Lage, LP Lima, MA Matos… - Experimental …, 2021 - Elsevier
Introduction Reduction in functional capacity is a negative clinical outcome of chronic
obstructive pulmonary disease (COPD). Studies have shown association between …

Cigarette Smoke Promotes Interleukin-8 Production in Alveolar Macrophages Through the Reactive Oxygen Species/Stromal Interaction Molecule 1/Ca2+ Axis

X Zhu, Y Zhan, Y Gu, Q Huang, T Wang… - Frontiers in …, 2021 - frontiersin.org
Chronic obstructive pulmonary disease (COPD), primarily attributed to cigarette smoke (CS),
is characterized by multiple pathophysiological changes, including oxidative stress and …

Time-course effects of aerobic physical training in the prevention of cigarette smoke-induced COPD

AC Toledo-Arruda, RP Vieira… - Journal of applied …, 2017 - journals.physiology.org
A previous study by our group showed that regular exercise training (ET) attenuated
pulmonary injury in an experimental model of chronic exposure to cigarette smoke (CS) in …

SIRT1 activity in peripheral blood mononuclear cells correlates with altered lung function in patients with chronic obstructive pulmonary disease

V Conti, G Corbi, V Manzo, P Malangone… - Oxidative medicine …, 2018 - Wiley Online Library
Background. Oxidative stress is a recognized pathogenic mechanism in chronic obstructive
pulmonary disease (COPD). Expression of the NAD+‐dependent deacetylase Sirtuin 1 …

Luteolin suppresses inflammation and oxidative stress in chronic obstructive pulmonary disease through inhibition of the NOX4‐mediated NF‐κB signaling pathway

M Li, H Wang, Y Lu, J Cai - Immunity, inflammation and disease, 2023 - Wiley Online Library
Introduction Chronic obstructive pulmonary disease (COPD) is associated with chronic
inflammation that predominantly affects the lung and peripheral airways. Previous …

Taurine treatment decreases inflammation and oxidative stress in lungs of adult mice exposed to cigarette smoke

C de Oliveira Ramos, KKD Campos… - Regulatory Toxicology …, 2018 - Elsevier
Taurine is the major free amino acid found in mammalian cells and is known to be an
antioxidant and membrane-stabilizing agent. This study aimed to evaluate the effects of …

NOX4‐Derived ROS Promotes Collagen I Deposition in Bronchial Smooth Muscle Cells by Activating Noncanonical p38MAPK/Akt‐Mediated TGF‐β Signaling

B Hao, R Sun, X Guo, L Zhang, J Cui… - Oxidative Medicine …, 2021 - Wiley Online Library
Background. Airway smooth muscle (ASM) remodeling is a hallmark in chronic obstructive
pulmonary disease (COPD). NADPH oxidase 4‐(NOX4‐) mediated reactive oxygen species …

Epithelial mitochondrial dysfunction in lung disease

L Zhang, W Wang, B Zhu, X Wang - Mitochondrial DNA and Diseases, 2017 - Springer
Since the twentieth century, scientists have studied the functions and mechanisms of the
mitochondria. The mitochondrion plays many important roles in cell functioning and …

[HTML][HTML] Особенности формирования и развития сердечно-сосудистых заболеваний у больных хронической обструктивной болезнью легких

НЮ Григорьева, МВ Майорова… - Терапевтический …, 2019 - cyberleninka.ru
Цель: изучение частоты встречаемости различных коморбидных и полиморбидных
состояний, а также особенностей клинического течения ишемической болезни сердца …

K63 ubiquitination of P21 can facilitate pellino-1 in the context of chronic obstructive pulmonary disease and lung cellular senescence

JH Ma, YT Zhang, LP Wang, QY Sun, H Zhang, JJ Li… - Cells, 2022 - mdpi.com
Chronic obstructive pulmonary diseases (COPD) is a kind of age-related, airflow-obstruction
disease mostly caused by cigarette smoke. However, the relationship between COPD and …