Neuropsychiatric (NP) involvement in Systemic Lupus Erythematosus (SLE), can be a
severe and troubling manifestation of the disease that heavily impacts patient's health …

The microbiome can be defined as the sum of the microbial and host's genome. Recent
information regarding this complex organ suggests that in animal models of multiple …

Introduction Studies investigating rates and risk factors for serious safety events (SSEs)
during rituximab treatment of multiple sclerosis (MS), neuromyelitis optica spectrum …

B cells mediate multiple sclerosis (MS) pathogenesis by mechanisms unrelated to
immunoglobulin (Ig). We reported that supernatants (Sup) from cultured B cells from blood of …

Multiple sclerosis (MS) is the prototypic complex disease, in which both genes and the
environment contribute to its pathogenesis. To date,> 200 independent loci across the …

B lymphocytes have essential roles in the autoimmune pathogenesis of multiple sclerosis
(MS). They regulate the autoimmune response and participate in the development of the …

Objective To characterize long-term repopulation of peripheral immune cells following
alemtuzumab-induced lymphopenia in relapsing-remitting MS (RRMS), with a focus on …

B cells play a vital function in multiple sclerosis (MS) pathogenesis through an array of
effector functions. All currently approved MS disease–modifying therapies alter the …

The etiological complexity of multiple sclerosis, an immune-mediated, neurodegenerative
disease with multifactorial etiology is still elusive because of an incomplete understanding of …

Autoimmune diseases are caused by self-immune responses to autoantigens, which
damage body tissues and severely affect the patient's quality of life. Therapeutic drugs are …