The basophil activation test (BAT) is a functional assay that measures the degree of
degranulation following stimulation with allergen or controls by flow cytometry. It correlates …

The basophil activation test (BAT) has become a pervasive test for allergic response through
the development of flow cytometry, discovery of activation markers such as CD 63 and …

Since the discovery of immunoglobulin E (IgE) as a mediator of allergic diseases in 1967,
our knowledge about the immunological mechanisms of IgE‐mediated allergies has …

Currently, testing for immunoglobulin E (IgE) sensitization is the cornerstone of diagnostic
evaluation in suspected allergic conditions. This review provides a thorough and updated …

Although the ideal type of reference would consist of a randomized, double-blind, placebo-
controlled study, the topic of this practice parameter is represented by very few such studies …

Background Oral food challenge (OFC) is the criterion standard to assess peanut allergy
(PA), but it involves a risk of allergic reactions of unpredictable severity. Objective Our aim …

Abstract Purpose of Review The basophil activation test (BAT) using flow cytometry has
supplanted traditional methods of measuring basophil degranulation using histamine and …

Various additives, including food colorants (FCs), are used in the food industry to make food
appealing to consumers and to add variety. Despite the widespread usage of FCs, adverse …

The incidence rate of anaphylaxis is increasing, particularly during the first 2 decades of life.
Common triggers include foods, medications, and insect stings. Clinical diagnosis is based …

Biomarkers of disease activity have come into wide use in the study of mechanisms of
human disease and in clinical medicine to both diagnose and predict disease course; as …