KRAS gene is involved in G protein-mediated signal transduction pathway and has
constitutive GTPase activity, which is a loss when the gene is mutated. It was reported that …

Considering that MAPK (mitogen-activated protein kinase) signaling pathway has an
important role in the progression of inflammatory cytokine secretion in type 2 diabetes …

Many studies have been conducted in the search for the mechanism underlying CNS-
oxygen toxicity (OT), which may be fatal when diving with a closed-circuit apparatus. We …

Transcription factor nuclear factor-erythroid-related factor 2 (NRF2) plays a central role in
cytoprotection from various environmental stresses. In unstressed conditions, kelch-like ECH …

Background Type 2 diabetes is commonly characterized by insulin deficiency and
decreased sensitivity of insulin receptors, leading to a chronic state of hyperglycemia in …

Purpose Hyperglycemia in type 2 diabetes mellitus increases inflammation through
pancreatic beta-cell destruction. Goat milk (kefir) and vitamin D3 have antioxidant and anti …

Diabetic complications may in part be due to inflammation. Diabetes can also develop in
non-obese people. Nonetheless, organ inflammation in non-obese type 2 diabetes mellitus …

Molecular basis of diabetes induced oxidative stress and immune dysfunction have not been
reported in animal science. The present study envisages same in subclinical diabetic (SCD) …

Background Diabetes mellitus causes low-grade chronic inflammation which leads to the
development of long-term complications. Oral magnesium (Mg) intake amongst other effects …

Metabolomics provides comprehensive investigation methods for profiling tissues or bodily
fluids. Metabolites show more expeditious fluctuations in response to a physiological …