Introduction Leukemia is an abnormal clonal development of leukemic cells originating from
the bone marrow, which is widely known for its significant prevalence and mortality rate …

Background In recent years, the incidence of hematological tumors has increased. The
tumor microenvironment (TME) is the local biological environment in the process of tumor …

The need for new therapeutic approaches to improve the response in acute leukemia (AL),
either by directing therapy or with new therapeutic alternatives, has been a research and …

Leukemia arising in the first year of life is generally referred to as infant leukemia. 1 Although
these age-defined malignancies are rare, infant leukemias are distinct from their …

Reference genes are used as internal reaction controls for gene expression analysis, and
for this reason, they are considered reliable and must meet several important criteria. In view …

The oral cavity is the place where the first symptoms of systemic diseases may appear.
Leukemia is the malignancy of the hematopoietic system in which abnormal leukocytes are …

Blood cancer occurs due to changes in white blood cells (WBCs). These changes are known
as leukemia. Leukemia occurs mostly in children and affects their tissues or plasma …

A number of systemic diseases including hematological disorders have manifestations in the
oral cavity region. These manifestations may often represent early signs of the underlying …

Leukemia is an abnormal proliferation of white blood cells in the bone marrow, resulting in a
large accumulation of abnormal leukemia cells in the blood and bone marrow. Hemorrhoids …

Cancer is understood to be a genetic disease. In pediatric leukemias, as in other cancer
types, genetic alterations lead to dysregulation of cellular processes and, ultimately, to …