The endothelium can evoke relaxations of the underlying vascular smooth muscle, by
releasing vasodilator substances. The best‐characterized endothelium‐derived relaxing …

The endothelium can evoke relaxations (dilatations) of the underlying vascular smooth
muscle, by releasing vasodilator substances. The best characterized endothelium‐derived …

It is well known that endothelium is the key vessel wall component in the initiation of the
atherogenic process. Its possible role in the later stages has been strongly suggested. 17 …

Nitric oxide (NO) is synthesised from l-arginine by the enzyme NO synthase (NOS). The
complex reaction involves the transfer of electrons from NADPH, via the flavins FAD and …

The endothelium causes relaxations of the underlying vascular smooth muscle, by releasing
nitric oxide (NO). The endothelial cells also can evoke hyperpolarization of the vascular …

Background—Exposure to risk factors such as hypertension or hypercholesterolemia
decreases the bioavailability of endothelium-derived nitric oxide (NO) and impairs …

In retrospect, basic research in the fields of nitric oxide (NO) and cyclic guanosine
monophosphate (cGMP) during the past two decades appears to have followed a logical …

Air pollution is consistently linked with elevations in cardiovascular disease (CVD) and CVD-
related mortality. Particulate matter (PM) is a critical factor in air pollution-associated CVD …

The inverse correlation between serum levels of high density lipoprotein (HDL) cholesterol
and the risk of coronary heart disease, the protection of susceptible animals from …

Over the past decade, clinical and basic research has demonstrated that estrogen has a
dramatic impact on the response to vascular injury and the development of atherosclerosis …