Antitumour dendritic cell vaccination in a priming and boosting approach

A Harari, M Graciotti, M Bassani-Sternberg… - Nature Reviews Drug …, 2020 - nature.com
Mobilizing antitumour immunity through vaccination potentially constitutes a powerful
anticancer strategy but has not yet provided robust clinical benefits in large patient …

Trial watch: Dendritic cell-based interventions for cancer therapy

L Galluzzi, L Senovilla, E Vacchelli, A Eggermont… - …, 2012 - Taylor & Francis
Dendritic cells (DCs) occupy a central position in the immune system, orchestrating a wide
repertoire of responses that span from the development of self-tolerance to the elicitation of …

Generation and characterisation of therapeutic tolerogenic dendritic cells for rheumatoid arthritis

RA Harry, AE Anderson, JD Isaacs… - Annals of the rheumatic …, 2010 - ard.bmj.com
Objectives Tolerogenic dendritic cells (tolDCs) constitute a promising experimental
treatment for targeting autoreactive T cells in autoimmune diseases, including rheumatoid …

Human dendritic cells in cancer

E Kvedaraite, F Ginhoux - Science immunology, 2022 - science.org
Dendritic cells (DCs) are professional antigen-presenting cells, orchestrating innate and
adaptive immunity during infections, autoimmune diseases, and malignancies. Since the …

[HTML][HTML] Dendritic cells the tumor microenvironment and the challenges for an effective antitumor vaccination

F Benencia, L Sprague, J McGinty, M Pate… - BioMed Research …, 2012 - hindawi.com
Many clinical trials have been carried out or are in progress to assess the therapeutic
potential of dendritic-cell-(DC-) based vaccines on cancer patients, and recently the first DC …

Induction of monocyte-to-dendritic cell maturation by extracorporeal photochemotherapy: initiation via direct platelet signaling

TS Durazzo, RE Tigelaar, R Filler, A Hayday… - … and Apheresis Science, 2014 - Elsevier
Extracorporeal Photochemotherapy (ECP) is a widely used therapy for cutaneous T cell
lymphoma (CTCL). Although the mechanism of clinical action of ECP is not precisely …

Cellular MRI as a suitable, sensitive non-invasive modality for correlating in vivo migratory efficiencies of different dendritic cell populations with subsequent …

S de Chickera, C Willert, C Mallet, R Foley… - International …, 2012 - academic.oup.com
The clinical application of dendritic cells (DC) as adjuvants in immunotherapies such as the
cell-based cancer vaccine continues to gain interest. The overall efficacy of this emerging …

[HTML][HTML] Focus: Skin: Extracorporeal Photochemotherapy: Mechanistic Insights Driving Recent Advances and Future Directions

BM Wei, D Hanlon, D Khalil, P Han… - The Yale Journal of …, 2020 - ncbi.nlm.nih.gov
Dendritic cells (DCs) are professional antigen-presenting cells, necessary for the initiation
and maintenance of antigen-specific immunity and tolerance. Decades of research have …

[PDF][PDF] Dendritic cells as therapeutic agents against cancer

EA Eksioglu, S Eisen, V Reddy - Front Biosci, 2010 - article.imrpress.com
Introduction 3. DC Immunobiology 4. Dendritic Cell Subpopulations 5. The type1/type 2
dualism and cancer 6. Generation of DC for Therapy 7. Consideration of DC Maturation …

Restoring immunosurveillance by dendritic cell vaccines and manipulation of the tumor microenvironment

A Vasaturo, M Verdoes, J de Vries, R Torensma… - Immunobiology, 2015 - Elsevier
Cancer cells evolve from normal cells throughout life and are usually recognized by our
immune system and destroyed, a process called immunosurveillance. Unfortunately, in …