From growing cells in spheroids to arranging them on complex engineered scaffolds, three-
dimensional cell culture protocols are rapidly expanding and diversifying. While these …

Patient-derived in vivo models of human cancer have become a reality, yet their turnaround
time is inadequate for clinical applications. Therefore, tailored ex vivo models that faithfully …

The efficiency of radiotherapy treatment regimes varies from tumour to tumour and from
patient to patient but it is generally highly influenced by the tumour microenvironment (TME) …

Cancer stem cells (CSCs) are crucial for tumorigenesis, metastasis, and therapy resistance
in esophageal squamous cell carcinoma (ESCC). To further elucidate the mechanism …

With a very low survival rate, pancreatic ductal adenocarcinoma (PDAC) is a deadly
disease. This has been primarily attributed to (i) its late diagnosis and (ii) its high resistance …

Pancreatic cancer is a devastating malignancy with minimal treatment options. Standard‐of‐
care therapy, including surgery and chemotherapy, is unsatisfactory, and therapies …

Simple Summary Pancreatic cancer challenges global health with non-specific symptoms,
devastatingly low survival rates, and high treatment resistance profiles. Tissue engineering …

Pancreatic ductal adenocarcinoma is an aggressive disease with an extremely low survival
rate. This is due to the (i) poor prognosis and (ii) high resistance of the disease to current …

Pancreatic ductal adenocarcinoma (PDAC) is a challenge for global health with very low
survival rate and high therapeutic resistance. Hence, advanced preclinical models for …

Simple Summary Epithelial Ovarian Cancer is considered to be a 'silent killer'and a
challenge for gynaecological health across the world due to its asymptotic nature in the early …