Simple Summary DNA structural biology deals with the understanding of DNA and three-
dimensional chromatin structure, which can determine its function in the cell. The key …

The chromatin of the human genome was analyzed at three DNA size levels. At the first,
compartment level, two “gene spaces” were found many years ago: A GC-rich, gene-rich …

Recent investigations have revealed 1) that the isochores of the human genome group into
two super‐families characterized by two different long‐range 3D structures, and 2) that these …

The standard genetic code determines that in most species, including viruses, there are 20
amino acids that are coded by 61 codons, while the other three codons are stop triplets …

The general model presented here for the formation of chromatin domains, LADs and TADs,
is primarily based on the 3-D structures of the corresponding DNA sequences, the GC-poor …

Genomes are characterized by large regions of homogeneous base compositions known as
isochores. The latter are divided into GC-poor and GC-rich classes linked to distinct …