Supramolecular photosensitizer enables oxygen-independent generation of hydroxyl radicals for photodynamic therapy

KX Teng, LY Niu, QZ Yang - Journal of the American Chemical …, 2023 - ACS Publications
The highly oxygen-dependent nature of photodynamic therapy (PDT) limits its therapeutic
efficacy against hypoxic solid tumors in clinics, which is an urgent problem to be solved …

Tumor-microenvironment-activatable organic phototheranostic agents for cancer therapy

S Zeng, Z Guo, Y Hao, YS Kafuti, Z Yang, Q Yao… - Coordination Chemistry …, 2024 - Elsevier
Tumor microenvironment is a rather unusual circumstances formed during the growth of
tumor cells, showing significant differences from normal cells and tissues. Indeed, many …

Recent Progress in Anti‐Tumor Nanodrugs Based on Tumor Microenvironment Redox Regulation

L Yao, X Zhu, Y Shan, L Zhang, J Yao, H Xiong - Small, 2024 - Wiley Online Library
The growth state of tumor cells is strictly affected by the specific abnormal redox status of the
tumor microenvironment (TME). Moreover, redox reactions at the biological level are also …

Localization of Cancer Cells for Subsequent Robust Photodynamic Therapy by ROS Responsive Polymeric Nanoparticles With Anti‐Metastasis Complexes NAMI‐A

H Zhang, M Cui, D Tang, B Wang, G Liang… - Advanced …, 2024 - Wiley Online Library
Photodynamic therapy (PDT), as a new type of light‐mediated reactive oxygen species
(ROS) cancer therapy, has the advantages of high therapeutic efficiency, non‐resistance …

Molecular engineering of AIE photosensitizers for inactivation of rabies virus

Y Bai, EY Yu, Y Liu, H Jin, X Liu, X Wu, M Zhang… - Small, 2023 - Wiley Online Library
Rabies is a zoonotic neurological disease caused by the rabies virus (RABV) that is fatal to
humans and animals. While several post‐infection treatment have been suggested …

Self‐Disassembling and Oxygen‐Generating Porphyrin‐Lipoprotein Nanoparticle for Targeted Glioblastoma Resection and Enhanced Photodynamic Therapy

Y Chen, Y Ma, K Shi, H Chen, X Han, C Wei… - Advanced …, 2024 - Wiley Online Library
The dismal prognosis for glioblastoma multiform (GBM) patients is primarily attributed to the
highly invasive tumor residual that remained after surgical intervention. The development of …

“Domino” cascade reactor based on DNA hydrogel for synergistic treatment of malignant tumor

X Liu, M Ma, S Tian, W Wang, X Li - European Journal of Medicinal …, 2023 - Elsevier
The action pathways of starvation therapy and photodynamic therapy (PDT) do not exist in
isolation and are usually related to tumor cell metabolism and immune regulation, which are …

Mitochondrial-targeted gold-doped porous carbon nanodots for combined photothermal and photodynamic therapy of breast cancer

L Zhang, M Yang, Q Li, Z Zhuang, X Sun… - ACS Applied Nano …, 2023 - ACS Publications
Mitochondrial homeostasis has been proved to be a potential oncology therapeutic target,
but there is still a huge technical challenge in developing an effective therapeutic regimen in …

Building in biologically appropriate multifunctionality in aqueous copper indium selenide-based quantum dots

X Yang, Y Li, P Zhang, L Guo, X Li, Y Shu, K Jiang… - Nanoscale, 2023 - pubs.rsc.org
Advanced nanoplatforms equipped with different functional moieties for theranostics hold
appealing promise for reshaping precision medicine. The reliable construction of an …

A NRF2 Regulated and the Immunosuppressive Microenvironment Reversed Nanoplatform for Cholangiocarcinoma Photodynamic‐Gas Therapy

W Wang, Y Gao, J Xu, T Zou, B Yang, S Hu… - Advanced …, 2024 - Wiley Online Library
Photodynamic therapy (PDT) is a minimally invasive and controllable local cancer treatment
for cholangiocarcinoma (CCA). However, the efficacy of PDT is hindered by intratumoral …