CRISPR/Cas9 genome editing has gained rapidly increasing attentions in recent years,
however, the translation of this biotechnology into therapy has been hindered by efficient …

Many psychiatric disorders, despite their specific characteristics, share deficits in the
cognitive domain including executive functions, emotional control and memory. However …

Mounting evidence suggests that storage has an impact on extracellular vesicles (EVs)
properties. While− 80° C storage is a widespread approach, some authors proposed …

The neuronal gene Arc is essential for long-lasting information storage in the mammalian
brain, mediates various forms of synaptic plasticity, and has been implicated in …

Excessive oxidative stress and inflammation are the key early events in the development of
intervertebral disc degeneration (IVDD). The NACHT, LRR, and PYD domain-containing …

Extracellular vesicles (EVs) are cell-derived membrane vesicles virtually secreted by all
cells, including brain cells. EVs are a major term that includes apoptotic bodies …

Cardiovascular disease (CVD) is a major cause of death in patients with chronic kidney
disease (CKD). Both conditions are rising in incidence as well as prevalence, creating poor …

In recent decades, cancer research has expanded exponentially beyond the study of
abnormally dividing cells to include complex and extensive heterotypic interactions between …

Intercellular signaling via extracellular vesicles (EVs) is an underappreciated modality of cell-
cell crosstalk that enables cells to convey packages of complex instructions to specific …

Retinal ischemia is a major cause of vision loss and impairment and a common underlying
mechanism associated with diseases such as glaucoma, diabetic retinopathy, and central …