Nucleophosmin (NPM1) is a mainly nucleolar protein that shuttles between nucleoli,
nucleoplasm and cytoplasm to fulfill its many functions. It is a chaperone of both nucleic …

ABSTRACT Nucleophosmin 1 (NPM1, also known as B23) is a multifunctional protein
involved in a variety of cellular processes, including ribosomal maturation, centrosome …

Specific C‐terminal nucleophosmin (NPM) mutations are related to the acute myeloid
leukaemia and cause mistargeting of mutated NPM (NPMmut) to the cytoplasm …

Simple Summary Nucleophosmin (NPM) is one of the most abundant nucleolar proteins and
its mutations frequently occur in acute myeloid leukemia (AML). The mutations cause …

Liver fibrosis is caused by a variety of chronic liver injuries and has caused significant
morbidity and mortality in the world with increasing tendency. Elucidation of the molecular …

Acute myeloid leukemia (AML) is a heterogeneous group of diseases classified into various
types on the basis of distinct features concerning the morphology, cytochemistry and …

Abstract Reactivating p53 and Inducing Tumor Apoptosis (RITA) has been reported to
increase the p53 activity and to trigger p53-dependent apoptosis in cancer cells with wild …

MATERIALS AND METHODS: Immunofluorescence was used to determine the intracellular
localization of NPM1 protein in wild-type (OCIAML2) and NPM1-mutated (OCI-AML3) AML …

Fluorescence lifetime imaging microscopy (FLIM) is a well-established technique with
numerous imaging applications. Yet, one of the limitations of FLIM is that it provides …

Enhanced green fluorescence protein (EGFP) is a fluorescent tag commonly used in cellular
and biomedical applications. Surprisingly, some interesting photochemical properties of …