Growth plate mechanics and mechanobiology. A survey of present understanding

I Villemure, IAF Stokes - Journal of biomechanics, 2009 - Elsevier
The longitudinal growth of long bones occurs in growth plates where chondrocytes
synthesize cartilage that is subsequently ossified. Altered growth and subsequent deformity …

[HTML][HTML] Neurologic correlates of gait abnormalities in cerebral palsy: implications for treatment

J Zhou, EE Butler, J Rose - Frontiers in human neuroscience, 2017 - frontiersin.org
Cerebral palsy (CP) is the most common movement disorder in children. A diagnosis of CP
is often made based on abnormal muscle tone or posture, a delay in reaching motor …

[HTML][HTML] Mechanical factors explain development of cam-type deformity

P Roels, R Agricola, EH Oei, H Weinans… - Osteoarthritis and …, 2014 - Elsevier
Objective A cam-type deformity drastically increases the risk of hip osteoarthritis (OA). Since
this type of skeletal anomaly is more prevalent among young active adults, it is hypothesized …

Long‐term effects of spasticity treatment, including selective dorsal rhizotomy, for individuals with cerebral palsy

BA MacWilliams, ML McMulkin, EA Duffy… - … Medicine & Child …, 2022 - Wiley Online Library
Aim To understand the long‐term effects of comprehensive spasticity treatment, including
selective dorsal rhizotomy (SDR), on individuals with spastic cerebral palsy. Method This …

[HTML][HTML] Intra-and inter-subject variability of femoral growth plate stresses in typically developing children and children with cerebral palsy

W Koller, B Gonçalves, A Baca, H Kainz - Frontiers in Bioengineering …, 2023 - frontiersin.org
Little is known about the influence of mechanical loading on growth plate stresses and
femoral growth. A multi-scale workflow based on musculoskeletal simulations and …

Computational model of endochondral ossification: Simulating growth of a long bone

SM Sadeghian, FD Shapiro, SJ Shefelbine - Bone, 2021 - Elsevier
Mechanical loading is a crucial factor in joint and bone development. Using a computational
model, we investigated the role of mechanics on cartilage growth rate, ossification of the …

Correlation between lower limb bone morphology and gait characteristics in children with spastic diplegic cerebral palsy

A Carriero, A Zavatsky, J Stebbins… - Journal of Pediatric …, 2009 - journals.lww.com
Background: Children with spastic diplegic cerebral palsy (CP) exhibit abnormal walking
patterns and frequently develop lower limb, long bone deformities. It is important to …

[HTML][HTML] Effect of growth plate geometry and growth direction on prediction of proximal femoral morphology

P Yadav, SJ Shefelbine, EM Gutierrez-Farewik - Journal of biomechanics, 2016 - Elsevier
Mechanical stimuli play a significant role in the process of endochondral growth. Thus far,
approaches to understand the endochondral mechanical growth rate have been limited to …

[HTML][HTML] ESB Clinical Biomechanics Award 2020: Pelvis and hip movement strategies discriminate typical and pathological femoral growth–Insights gained from a …

H Kainz, BA Killen, A Van Campenhout… - Clinical …, 2021 - Elsevier
Background Many children with cerebral palsy (CP) develop skeletal deformities during
childhood. So far, it is unknown why some children with CP develop bony deformities …

Mechanobiological prediction of proximal femoral deformities in children with cerebral palsy

A Carriero, I Jonkers, SJ Shefelbine - Computer methods in …, 2011 - Taylor & Francis
Children with cerebral palsy (CP) walk with altered gait and frequently exhibit proximal
femoral deformities, such as anteversion and coxa valga. The objective of this research was …