The coactivator peroxisome proliferator-activated receptor-gamma coactivator 1 α (PGC-1α)
coordinates a broad set of transcriptional programs that regulate the response of skeletal …

The process of tissue regeneration occurs in a developmentally timed manner, yet the role of
circadian timing is not understood. Here, we identify a role for the adult muscle stem cell …

The skeletal muscle phenotype is subject to considerable malleability depending on use.
Lowintensity endurance type exercise leads to qualitative changes of muscle tissue …

Altitude training has become very popular among athletes as a means to further increase
exercise performance at sea level or to acclimatize to competition at altitude. Several …

Exercise and oxidative stress research continues to grow as a physiological subdiscipline.
The influence of high altitude on exercise and oxidative stress is among the recent topics of …

Skeletal muscle is a large organ that accounts for up to half the total mass of the human
body. A progressive decline in muscle mass and strength occurs with ageing and in some …

Skeletal muscle undergoes metabolic remodelling in response to environmental hypoxia,
yet aspects of this process remain controversial. Broadly, environmental hypoxia has been …

Skeletal muscle utilizes both free fatty acids (FFAs) and glucose that circulate in the blood
stream. When blood glucose levels acutely increase, insulin stimulates muscle glucose …

Hypoxia refers to the decrease in oxygen tension in the tissues, and the central effector of
the hypoxic response is the transcription factor Hypoxia-Inducible Factor α (HIF1-α) …

Aims. The study investigated the effect of high‐intensity interval training in hypoxia and
normoxia on serum concentrations of proangiogenic factors, nitric oxide, and inflammatory …