The epidemiology, transmission, diagnosis, and management of drug-resistant tuberculosis—lessons from the South African experience
Drug-resistant tuberculosis (DR-TB) threatens to derail tuberculosis control efforts,
particularly in Africa where the disease remains out of control. The dogma that DR-TB …
particularly in Africa where the disease remains out of control. The dogma that DR-TB …
Diagnostic yield as an important metric for the evaluation of novel tuberculosis tests: rationale and guidance for future research
Better access to tuberculosis testing is a key priority for fighting tuberculosis, the leading
cause of infectious disease deaths in people. Despite the roll-out of molecular WHO …
cause of infectious disease deaths in people. Despite the roll-out of molecular WHO …
[HTML][HTML] Tuberculosis Variant with Rifampin Resistance Undetectable by Xpert MTB/RIF, Botswana
C Modongo, I Barilar, Q Wang, T Molefi… - Emerging Infectious …, 2023 - ncbi.nlm.nih.gov
GeneXpert MTB/RIF, a tool widely used for diagnosing tuberculosis, has limitations for
detecting rifampin resistance in certain variants. We report transmission of a pre–extensively …
detecting rifampin resistance in certain variants. We report transmission of a pre–extensively …
Global Burden of Tuberculosis in Adolescents and Young Adults: 1990–2019
W Shang, G Cao, W Jing, J Liu, W Liang, M Liu - Pediatrics, 2024 - publications.aap.org
OBJECTIVE Tuberculosis (TB) is a major health threat in adolescents and young adults.
However, its burden in this population remains unclear. This study aimed to assess TB …
However, its burden in this population remains unclear. This study aimed to assess TB …
An Effective Health System Approach to End TB: Implementing the Double X Strategy in Vietnam
AL Innes, V Lebrun, GL Hoang, A Martinez… - … Health: Science and …, 2024 - ghspjournal.org
Countries that are high burden for TB must reverse the COVID-19 pandemic's devastating
effects to accelerate progress toward ending TB. Vietnam's Double X (2X) strategy uses …
effects to accelerate progress toward ending TB. Vietnam's Double X (2X) strategy uses …
Innovative COVID-19 Point-of-Care Diagnostics Suitable for Tuberculosis Diagnosis: A Scoping Review
L Holtgrewe, S Jain, R Dekova, T Broger, C Isaacs… - medRxiv, 2024 - medrxiv.org
Introduction Rapid and accurate point-of-care (POC) tuberculosis (TB) diagnostics are a key
priority to close the TB diagnostic gap of 3.1 million people without a diagnosis. Leveraging …
priority to close the TB diagnostic gap of 3.1 million people without a diagnosis. Leveraging …
Expanding molecular diagnostic coverage for tuberculosis by combining computer-aided chest radiography and sputum specimen pooling: a modeling study from four …
Background In 2022, fewer than half of persons with tuberculosis (TB) have access to
molecular diagnostic tests for TB due to their high costs. Studies have found that computer …
molecular diagnostic tests for TB due to their high costs. Studies have found that computer …