Lipoprotein (a): a genetically determined, causal, and prevalent risk factor for atherosclerotic cardiovascular disease: a scientific statement from the American Heart …
G Reyes-Soffer, HN Ginsberg, L Berglund… - … , and vascular biology, 2022 - Am Heart Assoc
High levels of lipoprotein (a)[Lp (a)], an apoB100-containing lipoprotein, are an independent
and causal risk factor for atherosclerotic cardiovascular diseases through mechanisms …
and causal risk factor for atherosclerotic cardiovascular diseases through mechanisms …
Lipoprotein (a) and cardiovascular disease
PR Kamstrup - Clinical chemistry, 2021 - academic.oup.com
Background High lipoprotein (a) concentrations present in 10%–20% of the population have
long been linked to increased risk of ischemic cardiovascular disease. It is unclear whether …
long been linked to increased risk of ischemic cardiovascular disease. It is unclear whether …
Preclinical development and phase 1 trial of a novel siRNA targeting lipoprotein (a)
MJ Koren, PM Moriarty, SJ Baum, J Neutel… - Nature medicine, 2022 - nature.com
Compelling evidence supports a causal role for lipoprotein (a)(Lp (a)) in cardiovascular
disease. No pharmacotherapies directly targeting Lp (a) are currently available for clinical …
disease. No pharmacotherapies directly targeting Lp (a) are currently available for clinical …
Atualização da diretriz brasileira de dislipidemias e prevenção da aterosclerose–2017
AA Faludi, MCO Izar, JFK Saraiva… - Arquivos brasileiros de …, 2017 - SciELO Brasil
Material de distribuição exclusiva à classe médica. Os Arquivos Brasileiros de Cardiologia
não se responsabilizam pelo acesso indevido a seu conteúdo e que contrarie a …
não se responsabilizam pelo acesso indevido a seu conteúdo e que contrarie a …
A test in context: lipoprotein (a) diagnosis, prognosis, controversies, and emerging therapies
S Tsimikas - Journal of the American College of Cardiology, 2017 - jacc.org
Evidence that elevated lipoprotein (a)(Lp [a]) levels contribute to cardiovascular disease
(CVD) and calcific aortic valve stenosis (CAVS) is substantial. Development of isoform …
(CVD) and calcific aortic valve stenosis (CAVS) is substantial. Development of isoform …
Genetics of thoracic and abdominal aortic diseases: aneurysms, dissections, and ruptures
Dissections or ruptures of aortic aneurysms remain a leading cause of death in the
developed world, with the majority of deaths being preventable if individuals at risk are …
developed world, with the majority of deaths being preventable if individuals at risk are …
Structure, function, and genetics of lipoprotein (a)
K Schmidt, A Noureen, F Kronenberg… - Journal of lipid …, 2016 - ASBMB
Lipoprotein (a)[Lp (a)] has attracted the interest of researchers and physicians due to its
intriguing properties, including an intragenic multiallelic copy number variation in the LPA …
intriguing properties, including an intragenic multiallelic copy number variation in the LPA …
V Diretriz brasileira de dislipidemias e prevenção da aterosclerose
HT Xavier, MC Izar, JR Faria Neto… - Arquivos brasileiros de …, 2013 - SciELO Brasil
Material de distribuição exclusiva à classe médica. Os Arquivos Brasileiros de Cardiologia
não se responsabilizam pelo acesso indevido a seu conteúdo e que contrarie a …
não se responsabilizam pelo acesso indevido a seu conteúdo e que contrarie a …
Understanding the pathogenesis of abdominal aortic aneurysms
An aortic aneurysm is a dilatation in which the aortic diameter is≥ 3.0 cm. If left untreated,
the aortic wall continues to weaken and becomes unable to withstand the forces of the …
the aortic wall continues to weaken and becomes unable to withstand the forces of the …
Lipoprotein (a) concentration and risks of cardiovascular disease and diabetes
Abstract Background: Lipoprotein (a)[Lp (a)] is a causal risk factor for cardiovascular
diseases that has no established therapy. The attribute of Lp (a) that affects cardiovascular …
diseases that has no established therapy. The attribute of Lp (a) that affects cardiovascular …