[HTML][HTML] Importance of Metalloproteinase 8 (MMP-8) in the Diagnosis of Periodontitis

EA Zalewska, R Ławicka, P Grygorczuk… - International Journal of …, 2024 - mdpi.com
Periodontitis is a complex condition. Left untreated, it leads to tooth loss and the need for
prosthetic treatment. The incidence of periodontitis is steadily increasing, so new methods …

Evaluating anticancer activity of emodin by enhancing antioxidant activities and affecting PKC/ADAMTS4 pathway in thioacetamide-induced hepatocellular carcinoma …

HM Hassan, AM Hamdan, A Alattar, R Alshaman… - Redox …, 2024 - Taylor & Francis
Emodin is a naturally occurring anthraquinone derivative with a wide range of
pharmacological activities, including neuroprotective and anti-inflammatory activities. We …

[HTML][HTML] Diagnostic Utility of Selected Matrix Metalloproteinases (MMP-2, MMP-3, MMP-11, MMP-26), HE4, CA125 and ROMA Algorithm in Diagnosis of Ovarian …

A Kicman, E Gacuta, M Kulesza… - International Journal of …, 2024 - mdpi.com
Ovarian cancer (OC) has an unfavorable prognosis. Due to the lack of effective screening
tests, new diagnostic methods are being sought to detect OC earlier. The aim of this study …

[HTML][HTML] Importance of Metalloproteinase Enzyme Group in Selected Skeletal System Diseases

M Kulesza, A Kicman, J Motyka, T Guszczyn… - International Journal of …, 2023 - mdpi.com
Bone tissue is a dynamic structure that is involved in maintaining the homeostasis of the
body due to its multidirectional functions, such as its protective, endocrine, or immunological …

Anticancer activities of Brachydin C in human prostate tumor cells (DU145) grown in 2D and 3D models: Stimulation of cell death and downregulation of …

LCB Oliveira, DL Ribeiro… - Chemical Biology & …, 2022 - Wiley Online Library
Brachydin C (BrC) has demonstrated in vitro cytotoxic and antiproliferative effects in prostate
cancer cells. In the present study, we compare the anticancer effects of BrC in DU145 cells …

Antiapoptotic and pro-metastatic roles of cytokine FAM3B in triple-negative breast cancer

IDS Caldeira, G Giovanini, LF Adorno, D Fernandes… - Clinical Breast …, 2024 - Elsevier
Background Triple-negative breast cancer (TNBC) is the most aggressive subtype of breast
cancer. FAM3B, a secreted protein, has been extensively studied in various types of tumors …

Polymorphisms and gene expression of metalloproteinases and their inhibitors associated with cerebral ischemic stroke in young patients with sickle cell anemia

Ó do Kleyton Palmeira, AK da Silva Freire… - Molecular Biology …, 2023 - Springer
Background Sickle cell anemia (SCA) is a genetic disease with great clinical heterogeneity
and few viable strategies for treatment; hydroxyurea (HU) is the only widely used drug. Thus …

[HTML][HTML] The Potential of Extracellular Matrix-and Integrin Adhesion Complex-Related Molecules for Prostate Cancer Biomarker Discovery

I Samaržija - Biomedicines, 2023 - mdpi.com
Prostate cancer is among the top five cancer types according to incidence and mortality. One
of the main obstacles in prostate cancer management is the inability to foresee its course …

The expression and localization of selected matrix metalloproteinases (MMP-2,-7 and-9) and their tissue inhibitors (TIMP-2 and-3) in follicular cysts of sows

M Grzesiak, K Kaminska, K Knapczyk-Stwora, A Hrabia - Theriogenology, 2022 - Elsevier
Matrix metalloproteinases (MMPs) are a family of enzymes that degrade extracellular matrix
(ECM) molecules, playing a vital role in tissue remodeling under physiological and …

[HTML][HTML] Risk Association of TOX3 and MMP7 Gene Polymorphisms with Sporadic Breast Cancer in Mexican Women

O Solis-Coronado, MP Villarreal-Vela… - Current …, 2022 - mdpi.com
Breast cancer (BC) has one of the highest incidences and mortality worldwide. Single
nucleotide polymorphisms (SNPs) in TOX3 rs3803662 and MMP7 rs1943779 have been …