TRIM47 silencing inhibits the malignant biological behaviors of prostate cancer cells by regulating MDM2/p53 signaling

C Wang, R Chang, J Li, L Li - Cell Biochemistry and Biophysics, 2024 - Springer
Prostate cancer (PCa) is a prevalent male malignancy globally. Tripartite motif 47 (TRIM47)
has been reported to be associated with PCa. However, how TRIM47 acts on PCa is still …

BRAF V600E mutation mediates invasive and growth features in ameloblastoma

CX Zhang, LZ Zhang, H Lin, QW Man, B Liu - Oral Diseases, 2024 - Wiley Online Library
Objectives Ameloblastoma (AM), a locally aggressive tumor with extensive growth capacity,
causes significant damage to the jaw and affects facial appearance. Although the high …

MMP-3 -1171 5A/6A promoter polymorphism and cancer susceptibility: an updated meta-analysis and trial sequential analysis

MA Aziz, S Jafrin, MA Barek, SN Anonna… - Future Oncology, 2023 - Taylor & Francis
Purpose: Previous studies of MMP-3-1171 5A/6A in cancers have produced inconclusive
outcomes. This updated meta-analysis was performed to clarify the link between this variant …

MT1‐MMP and TIMP‐2 are first expressed in the colon glands after a single dose of azoxymethane (AOM)

J da Silva, JR Freitas, ER do Carmo… - The Anatomical …, 2024 - Wiley Online Library
Tissue inhibitor of metalloproteinase‐2 (TIMP‐2) and membrane‐type 1‐matrix
metalloproteinase (MT1‐MMP) are always expressed during the cancer process. The aim …

[HTML][HTML] Changes in Rat Mammary Tissue Architecture Following Pregnancy/Lactation Exposure to Glyphosate Alone or with 2, 4-D and Dicamba

AE Cirstea, AO Docea, L Cercelaru… - Current Health …, 2024 - ncbi.nlm.nih.gov
The current study aimed to assess the possible endocrine disruptor effects on rat mammary
tissue and reproductive organs during pregnancy and lactation when exposed to low doses …

MMP11 and MMP17 are potential biomarkers for uterine corpus endometrial carcinoma prognosis

Y Zhang, J Wang, Y Fan, F Lang, F Fu, Q Liu - Clinical and Translational …, 2024 - Springer
Background Matrix metalloproteinases (MMP) are important proteases that degrade the
extracellular matrix (ECM) and thus essentially mediate tumor vascularization, metastasis …

Anti-CD47 immunotherapy as a therapeutic strategy for the treatment of breast cancer brain metastasis

JD Mackert, ER Stirling, AS Wilson, B Westwood… - bioRxiv, 2023 - biorxiv.org
The presence of cell surface protein CD47 allows cancer cells to evade innate and adaptive
immune surveillance resulting in metastatic spread. CD47 binds to and activates SIRPα on …

Demethoxycurcumin inhibits the cell migration and MMP-2 expression in human retinal pigment epithelial cells by targeting the STAT-3 pathway

K Wang, PN Chen, HW Chien, YH Hsieh… - Experimental Eye …, 2021 - Elsevier
Proliferative vitreoretinopathy (PVR) involves retinal pigment epithelium (RPE) cell
proliferation and migration and leads to tractional retinal detachment. Demethoxycurcumin …

Autophagy promotes invadopodia formation in human ovarian cancer cells via the p62-extracellular signal-regulated kinase 1/2 pathway

Z Zhou, J Zhao, Y Liu, X Yan… - Experimental and …, 2021 - spandidos-publications.com
Invasiveness and metastatic potential are among the most essential characteristics of
malignant tumors. Furthermore, it has been reported that autophagy and invasion are …

Invasion und Metastasierung

WA Schulz - Molekularbiologie menschlicher Krebserkrankungen, 2024 - Springer
Zusammenfassung Dieses Kapitel beschreibt Prozesse, Moleküle und Wechselwirkungen,
die zur Invasion und Metastasierung beitragen, die am stärksten definierenden …