[HTML][HTML] Pathophysiology of atherosclerosis

S Jebari-Benslaiman, U Galicia-García… - International journal of …, 2022 - mdpi.com
Atherosclerosis is the main risk factor for cardiovascular disease (CVD), which is the leading
cause of mortality worldwide. Atherosclerosis is initiated by endothelium activation and …

[HTML][HTML] Redox regulation of the immune response

G Morris, M Gevezova, V Sarafian… - Cellular & Molecular …, 2022 - nature.com
The immune-inflammatory response is associated with increased nitro-oxidative stress. The
aim of this mechanistic review is to examine:(a) the role of redox-sensitive transcription …

How oxidized low-density lipoprotein activates inflammatory responses

JP Rhoads, AS Major - Critical Reviews™ in Immunology, 2018 - dl.begellhouse.com
Cardiovascular disease (CVD) is the number one cause of death in the United States and
worldwide. The most common cause of cardiovascular disease is atherosclerosis, or …

[PDF][PDF] Inflammatory biomarkers of coronary heart disease

H Li, K Sun, R Zhao, J Hu, Z Hao, F Wang… - … Biosci (Schol Ed), 2018 - article.imrpress.com
Introduction 3. Characteristics of atherosclerosis 4. Inflammation cascade involved the
development of atherosclerosis and CHD 5. Predictive inflammatory biomarkers in CHD 5.1 …

Oxidative theory of atherosclerosis and antioxidants

R Salvayre, A Negre-Salvayre, C Camaré - Biochimie, 2016 - Elsevier
Atherosclerosis is a multifactorial process that begins early in infancy and affects all the
humans. Early steps of atherogenesis and the evolution towards complex atherosclerotic …

[HTML][HTML] Signaling pathways and key genes involved in regulation of foam cell formation in atherosclerosis

AV Poznyak, WK Wu, AA Melnichenko, R Wetzker… - Cells, 2020 - mdpi.com
Atherosclerosis is associated with acute cardiovascular conditions, such as ischemic heart
disease, myocardial infarction, and stroke, and is the leading cause of morbidity and …

Follicular B cells promote atherosclerosis via T cell–mediated differentiation into plasma cells and secreting pathogenic immunoglobulin G

C Tay, YH Liu, P Kanellakis, A Kallies, Y Li… - … , and vascular biology, 2018 - Am Heart Assoc
Objective—B cells promote or protect development of atherosclerosis. In this study, we
examined the role of MHCII (major histocompatibility II), CD40 (cluster of differentiation 40) …

[HTML][HTML] Oxidized low-density lipoprotein immune complex priming of the Nlrp3 inflammasome involves TLR and FcγR cooperation and is dependent on CARD9

JP Rhoads, JR Lukens, AJ Wilhelm… - The Journal of …, 2017 - journals.aai.org
Oxidized low-density lipoprotein (oxLDL) is known to activate inflammatory responses in a
variety of cells, especially macrophages and dendritic cells. Interestingly, much of the oxLDL …

[HTML][HTML] Mitochondrial dysfunction in vascular wall cells and its role in atherosclerosis

D Salnikova, V Orekhova, A Grechko… - International Journal of …, 2021 - mdpi.com
Altered mitochondrial function is currently recognized as an important factor in
atherosclerosis initiation and progression. Mitochondrial dysfunction can be caused by …

[HTML][HTML] Medicinal plants as a potential and successful treatment option in the context of atherosclerosis

TV Kirichenko, VN Sukhorukov, AM Markin… - Frontiers in …, 2020 - frontiersin.org
Atherosclerosis is a chronic multifactorial disease characterized by mainly changes of blood
lipids profile and inflammation in vessel wall. The cardiovascular disease based on …