Unicellular eukaryotes of the genus Leishmania are collectively responsible for a
heterogeneous group of diseases known as leishmaniasis. The visceral form of …

The mechanisms underlying the failure to control the growth and systemic spread of
Leishmania parasites in human visceral leishmaniasis (VL) are not well understood …

Visceral Leishmaniasis (VL) is the most fatal form of disease leishmaniasis. To date, there
are no effective prophylactic measures and therapeutics available against VL. Recently, new …

Although leishmaniases are endemic in 98 countries, they are still considered neglected
tropical diseases. Leishmaniases are characterized by the emergence of new virulent and …

Introduction Leishmaniasis is a major public health problem and the second most lethal
parasitic disease in the world due to the lack of effective treatments and vaccines. Even …

Diseases caused by insect borne trypanosomatid parasites are significant, yet remain a
neglected public health problem. Leishmania, a unicellular protozoan parasite is the …

Experimental visceral leishmaniasis (VL) caused by infection with Leishmania donovani
results in the development of organ‐specific immunity in the two main target tissues of …

Leishmania parasites have been widely used in experimental models to understand
generation, maintenance and failure of immune responses underlying resistance and …

Visceral leishmaniasis is a chronic parasitic disease associated with severe immune
dysfunction. Treatment options are limited to relatively toxic drugs, and there is no vaccine …

Susceptibility to infectious disease is influenced by multiple host genes, most of which are
low penetrance QTLs that are difficult to map in humans. Leishmaniasis is a well-studied …