The purpose of the lens is to project a sharply focused, undistorted image of the visual
surround onto the neural retina. The first pre-requisite, therefore, is that the tissue should be …

Lens opacities, or cataract (s), may be inherited as a classic Mendelian disorder usually with
early-onset or, more commonly, acquired with age as a multi-factorial or complex trait. Many …

Intermediate filaments (IFs) are a key component of the cytoskeleton in virtually all vertebrate
cells, including those of the lens of the eye. IFs help integrate individual cells into their …

Background Cellular differentiation is marked by temporally and spatially coordinated gene
expression regulated at multiple levels. DNA methylation represents a universal mechanism …

Purpose Fiber cells of the ocular lens are bounded by a highly specialized plasma
membrane. Despite the pivotal role that membrane proteins play in the physiology and …

Posterior capsular opacification (PCO) is the major complication arising after cataract
treatment. PCO occurs when the lens epithelial cells remaining following surgery (LC s) …

Fibrotic posterior capsular opacification (PCO), one of the major complications of cataract
surgery, occurs when lens epithelial cells (LCs) left behind post cataract surgery (PCS) …

Congenital cataracts are a major cause of induced blindness in children, and inherited
cataracts are the major cause of congenital cataracts. Inherited congenital cataracts have …

Purpose The ocular lens contains only two cell types: epithelial cells and fiber cells. The
epithelial cells lining the anterior hemisphere have the capacity to continuously proliferate …

Worldwide 20,000–40,000 children with congenital or childhood cataract are born every
year with varying degrees and patterns of lens opacification with a broad aetiology. In most …