Resveratrol: a review of preclinical studies for human cancer prevention

M Athar, JH Back, X Tang, KH Kim, L Kopelovich… - Toxicology and applied …, 2007 - Elsevier
The search for novel and effective cancer chemopreventive agents has led to the
identification of various naturally occurring compounds one of which is resveratrol (trans-3 …

Chemoprevention of cancer

MB Sporn, N Suh - Carcinogenesis, 2000 - academic.oup.com
In this short article, we review the conceptual basis for chemoprevention of cancer, the
proven clinical efficacy of this concept, and current trends to develop new chemopreventive …

Squalene: potential chemopreventive agent

TJ Smith - Expert opinion on investigational drugs, 2000 - Taylor & Francis
Squalene is a triterpene that is an intermediate of the cholesterol biosynthesis pathway and
it can be obtained from the diet. Olive oil contains 0.2-0.7% squalene. The average intake of …

Preclinical and clinical evaluation of sulforaphane for chemoprevention in the breast

BS Cornblatt, L Ye, AT Dinkova-Kostova, M Erb… - …, 2007 - academic.oup.com
Consumers of higher levels of Brassica vegetables, particularly those of the genus Brassica
(broccoli, Brussels sprouts and cabbage), reduce their susceptibility to cancer at a variety of …

Mechanisms of N-acetylcysteine in the prevention of DNA damage and cancer, with special reference to smoking-related end-points

S De Flora, A Izzotti, F D'Agostini… - …, 2001 - academic.oup.com
Although smoking cessation is the primary goal for the control of cancer and other smoking-
related diseases, chemoprevention provides a complementary approach applicable to high …

Ins and outs of dietary phytochemicals in cancer chemoprevention

GL Russo - Biochemical pharmacology, 2007 - Elsevier
A voluminous number of evidence suggests that an increased consumption of fruit and
vegetables is a relatively easy and practical strategy to reduce significantly the incidence of …

Chemoprevention: an essential approach to controlling cancer

MB Sporn, N Suh - Nature Reviews Cancer, 2002 - nature.com
Mortality that results from the common forms of cancer is still unacceptably high. Despite
immense advances in the understanding of the mechanisms of carcinogenesis, in bringing …

Mechanisms of combined action of different chemopreventive dietary compounds: a review

TM de Kok, SG van Breda, MM Manson - European journal of nutrition, 2008 - Springer
Consumption of fruits and vegetables has generally been associated with a decrease in
cancer incidence and cardiovascular disease. Over the years, numerous bioactive …

Importance of phase 2 gene regulation in protection against electrophile and reactive oxygen toxicity and carcinogenesis

P Talalay, AT Dinkova-Kostova… - Advances in enzyme …, 2003 - Elsevier
Tumor cells are monoclonal descendants of normal cells. They arise by a prolonged (often
several decades) multistage process comprising the accumulation of damaging genetic and …

Phytochemicals in cancer prevention and therapy: truth or dare?

M Russo, C Spagnuolo, I Tedesco, GL Russo - Toxins, 2010 - mdpi.com
A voluminous literature suggests that an increase in consumption of fruit and vegetables is a
relatively easy and practical strategy to reduce significantly the incidence of cancer. The …