Withdrawal symptoms commonly occur during tapering and/or after discontinuation of
antidepressant drugs, particularly selective serotonin reuptake inhibitors and serotonin …

Background: Affective disturbances involving alterations of mood, anxiety and irritability may
be early symptoms of medical illnesses. The aim of this paper was to provide a systematic …

Benzodiazepines (BDZs) continue to be shrouded in controversy, mainly because of
dependence associated with their long-term use and some of their side effects. Despite …

Background: It is unclear whether antidepressants can prevent suicides or suicide attempts,
particularly during long-term use. Methods: We carried out a comprehensive review of long …

Scholten et al.[1] reported on the first randomized controlled trial that attempted to prevent
relapse in patients with remitted anxiety disorder who discontinued antidepressant drugs …

The objective of this study was to investigate the current status and trends in antidepressant
use and expenditure in China from 2013 to 2018. The study had a retrospective design …

In the past decade, the number of papers dealing with treatment resistance in depression
has increased to a considerable degree. It has recently been discussed whether current …

The re-emergence (ie 'breakthrough') of depressive symptoms despite maintenance
treatment of depression with antidepressant drugs is a complex clinical phenomenon …

Background: Second-generation antipsychotic drugs (SGAs) are increasingly administered
to achieve weight gain in anorexia nervosa. In this meta-analysis, we aimed to determine if …

Background In current psychiatric practice, antidepressants are widely and with ever-
increasing frequency prescribed to patients. However, several scientific biases obfuscate …