PAICS as a potential target for cancer therapy linking purine biosynthesis to cancer progression

A Huo, X Xiong - Life Sciences, 2023 - Elsevier
Tumor cells are required to undergo metabolic reprogramming for rapid development and
progression, and one of the metabolic characteristics of cancer cells is the excessive …

Crosstalk between Endothelial Cells and Tumor Cells: A New Era in Prostate Cancer Progression

S Ji, W Wu, Q Jiang - International Journal of Molecular Sciences, 2023 - mdpi.com
Prostate cancer stands as one of the most prevalent malignancies afflicting men worldwide.
The tumor microenvironment plays a pivotal role in tumor progression, comprising various …

P2Y2-P2X7 receptors cross-talk in primed mesenteric endothelial cells upregulates NF-κB signaling favoring mononuclear cell adhesion in schistosomiasis

NF Oliveira, MMLV Monteiro, NS Mainieri… - Frontiers in …, 2024 - frontiersin.org
Schistosomiasis is an intravascular infectious disease that impacts over 200 million people
globally. In its chronic stage, it leads to mesenteric inflammation with significant involvement …