The Complex Connection between Obesity and Cancer: Signaling Pathways and Therapeutic Implications
Obesity has emerged as an important global health challenge, significantly influencing the
incidence and progression of various cancers. This comprehensive review elucidates the …
incidence and progression of various cancers. This comprehensive review elucidates the …
Targeting PI3K/AKT/mTOR Signaling to Overcome Drug Resistance in Cancer
M Tufail, WD Wan, C Jiang, N Li - Chemico-Biological Interactions, 2024 - Elsevier
This review comprehensively explores the challenge of drug resistance in cancer by
focusing on the pivotal PI3K/AKT/mTOR pathway, elucidating its role in oncogenesis and …
focusing on the pivotal PI3K/AKT/mTOR pathway, elucidating its role in oncogenesis and …
[HTML][HTML] Inverse FASN and LDHA correlation drives metabolic resistance in breast cancer
C Papulino, U Chianese, A Ali, G Favale… - Journal of Translational …, 2024 - Springer
Background Breast cancer manifests as a heterogeneous pathology marked by complex
metabolic reprogramming essential to satisfy its energy demands. Oncogenic signals boost …
metabolic reprogramming essential to satisfy its energy demands. Oncogenic signals boost …
[HTML][HTML] Identification of breast cancer-associated PIK3CA H1047R mutation in blood circulation using an asymmetric PCR assay
DT Thao, NP Thanh, DV Quyen, LT Khai, LH Song… - Plos one, 2024 - journals.plos.org
Purpose To establish a highly sensitive and specific approach for the detection of circulating
PIK3CA H1047R mutation in breast cancer (BC) patients and to investigate the association …
PIK3CA H1047R mutation in breast cancer (BC) patients and to investigate the association …
Hallmarks of cancer resistance
M Tufail, JJ Hu, J Liang, CY He, WD Wan, YQ Huang… - Iscience, 2024 - cell.com
This review explores the hallmarks of cancer resistance, including drug efflux mediated by
ATP-binding cassette (ABC) transporters, metabolic reprogramming characterized by the …
ATP-binding cassette (ABC) transporters, metabolic reprogramming characterized by the …
Analysis of PIK3CA mutations in the primary and recurrent tumors of hormone receptor positive/human epidermal growth factor receptor 2 negative breast cancer
Y Wang, X Li, S Zhang, L Liang, L Xu… - Japanese Journal of …, 2024 - academic.oup.com
Objective Our aim was to compare the PIK3CA mutation status in matched primary and
recurrent tumors of hormone receptor positive/human epidermal growth factor receptor 2 …
recurrent tumors of hormone receptor positive/human epidermal growth factor receptor 2 …
Enhancing breast cancer treatment through pharmacogenomics: A narrative review
RMR Kumar, S Joghee - Clinica Chimica Acta, 2024 - Elsevier
Pharmacogenomics has become integral to personalised medicine in breast cancer,
utilising genetic insights to customize treatment strategies and enhance patient outcomes …
utilising genetic insights to customize treatment strategies and enhance patient outcomes …
[HTML][HTML] Cancer Patient-Derived Cell-Based Models: Applications and Challenges in Functional Precision Medicine
J Dinić, S Jovanović Stojanov, M Dragoj, M Grozdanić… - Life, 2024 - mdpi.com
The field of oncology has witnessed remarkable progress in personalized cancer therapy.
Functional precision medicine has emerged as a promising avenue for achieving superior …
Functional precision medicine has emerged as a promising avenue for achieving superior …
[PDF][PDF] The Role of Platelet-Rich Plasma in the Management of Sensorineural Hearing Loss: Current Evidence and Emerging Trends
CV Singh, S Jain - Cureus, 2024 - cureus.com
Sensorineural hearing loss (SNHL) is a common form of hearing impairment characterized
by damage to the inner ear or auditory nerve, resulting in significant communication …
by damage to the inner ear or auditory nerve, resulting in significant communication …
Utilizing Machine Learning Techniques for Accurate Diagnosis of Breast Cancer and Comprehensive Statistical Analysis of Clinical Data
MEE Phyo - 2024 - search.proquest.com
Breast cancer represents a formidable malignancy, presenting a substantial threat to global
health and individual well-being. Conventionally, it is widely held that the prognosis for …
health and individual well-being. Conventionally, it is widely held that the prognosis for …