Adenosine has been reported to stimulate or inhibit the release of angiogenic factors
depending on the cell type examined. To test the hypothesis that differential expression of …

Recent evidence indicates that topical application of adenosine A2A receptor agonists,
unlike growth factors, increases the rate at which wounds close in normal animals and …

The brain immune system, which consists mainly of astrocytes, microglia and infiltrating
immune cells, is quiescent normally, but it is activated in response to pathophysiological …

Development of neuronal and glial cells and their maintenance are under control of
neurotrophic factors (NTFs). An exogenous administration of NTFs protects extremely …

Both advanced glycation end products and vascular endothelial growth factor are believed
to play a role in the pathogenesis of diabetic retinopathy. It is known that vascular …

Adenosine is released during tissue injury, ischemia and tumor growth, and promotes
angiogenesis. Because mast cells accumulate in the proximity of new blood vessel …

The importance of metabolic factors in the regulation of angiogenesis is well understood. An
increase in metabolic activity leads to a decrease in tissue oxygenation causing tissues to …

Under normoxic conditions, macrophages from C57BL mice produce low levels of vascular
endothelial growth factor (VEGF). Hypoxia stimulates VEGF expression by∼ 500%; …

The microvasculature is an extremely adaptable structure that is capable of architectural and
functional adjustments in response to multiple biochemical and mechanical stimuli …

Vascular endothelial growth factor (VEGF) is a potent mitogen for endothelial cells and a
vascular permeability factor. In this study we found that the addition of angiotensin II (AII) to …