Implication of the hypoxia response element of the Vegf promoter in mouse models of retinal and choroidal neovascularization, but not retinal vascular development

SA Vinores, WH Xiao, S Aslam, J Shen… - Journal of cellular …, 2006 - Wiley Online Library
Retinal neovascularization (NV) and macular edema, resulting from blood‐retinal barrier
(BRB) breakdown, are major causes of visual loss in ischemic retinopathies. Choroidal NV …

Angiogenic factors in the central nervous system

MR Harrigan - Neurosurgery, 2003 - journals.lww.com
Abstract THE PAST DECADE has seen considerable advances in the understanding of
angiogenesis. Blood vessel development and growth in the central nervous system are …

Localization of adenosine receptor messenger RNAs in the rat eye

A Kvanta, S SEREGARD, S SEJERSEN, B KULL… - Experimental eye …, 1997 - Elsevier
Adenosine is present in all cells and body fluids and has been suggested to play several
roles in the physiology of ocular tissues. The present study was undertaken to determine …

Enhanced expression of vascular endothelial growth factor in lungs of newborn infants with congenital diaphragmatic hernia and pulmonary hypertension

SMK Shehata, WJ Mooi, T Okazaki, I El-Banna… - Thorax, 1999 - thorax.bmj.com
BACKGROUND Pulmonary hypoplasia accompanied by pulmonary hypertension resistant
to treatment is an important feature of congenital diaphragmatic hernia (CDH). The …

Hypoxia upregulates glucose transport activity through an adenosine-mediated increase of GLUT1 expression in retinal capillary endothelial cells.

H Takagi, GL King, LP Aiello - Diabetes, 1998 - Am Diabetes Assoc
Elevation of intracellular glucose within retinal vascular cells is believed to be an important
causal factor in the development of diabetic retinopathy. The intracellular glucose …

Adenosine receptors in wound healing, fibrosis and angiogenesis

I Feoktistov, I Biaggioni, BN Cronstein - Adenosine receptors in health and …, 2009 - Springer
Wound healing and tissue repair are critical processes, and adenosine, released from
injured or ischemic tissues, plays an important role in promoting wound healing and tissue …

Stimulation of expression for the adenosine A2A receptor gene by hypoxia in PC12 cells: a potential role in cell protection

S Kobayashi, DE Millhorn - Journal of Biological Chemistry, 1999 - ASBMB
The purpose of this study was to examine the regulation of adenosine A2A receptor (A2AR)
gene expression during hypoxia in pheochromocytoma (PC12) cells. Northern blot analysis …

Vascular and neuronal protection in the developing retina: potential therapeutic targets for retinopathy of prematurity

JKW Tsang, J Liu, ACY Lo - International journal of molecular sciences, 2019 - mdpi.com
Retinopathy of prematurity (ROP) is a common retinal disease in preterm babies. To prolong
the lives of preterm babies, high oxygen is provided to mimic the oxygen level in the …

[PDF][PDF] Angiogenesis and the ischaemic heart

R Tabibiazar, SG Rockson - European heart journal, 2001 - cardiacos.net
Historically, interest in the therapeutic implications of angiogenesis has centered on the
inhibition of new vascular growth to retard the spread of cancer [1, 2]. More recently …

Dual control of vascular tone and remodelling by ATP released from nerves and endothelial cells

G Burnstock - Pharmacological Reports, 2008 - discovery.ucl.ac.uk
Purinergic signalling is important both in short-term control of vascular tone and in longer-
term control of cell proliferation, migration and death involved in vascular remodelling. There …