Publisher Summary This chapter considers two aspects of alpha-herpesvirus pathogenesis:
the invasion and spread of two representative viruses, herpes simplex virus (HSV) and …

Much of our present understanding of the function and operation of the basal ganglia rests
on models of anatomical connectivity derived from tract-tracing approaches in rodents and …

It has become widely appreciated that the spinal cord has significant neuroplastic potential,
is not hard-wired, and that with traumatic injury and anatomical plasticity, the networks that …

The suprachiasmatic nucleus (SCN) of the hypothalamus, the principal circadian
pacemaker, is a paired structure with two subdivisions, a ventral core receiving photic input …

Retrograde transneuronal tracing with rabies virus from the right orbicularis oculi muscle
was used to identify neural networks underlying spontaneous, reflex, and learned blinks …

Background The kidneys critically contribute to body homeostasis under the control of the
autonomic nerves, which enter the kidney along the renal vasculature. Although the renal …

The nontoxic proteolytic C fragment of tetanus toxin (TTC peptide) has the same ability to
bind nerve cells and be retrogradely transported through a synapse as the native toxin. We …

Gene transfer of tyrosine hydroxylase (TH) in animal models of Parkinson's disease (PD),
using either genetically modified cells or recombinant virus vectors, has produced partial …

The pseudorabies virus (PRV) gE gene encodes a multifunctional membrane protein found
in infected cell membranes and in the virion envelope. Deletion of the gE gene results in …

Gonadal functions are governed by the hypothalamohypophysial system. Recent studies
have demonstrated the existence of a multisynaptic neural pathway between the brain and …