Developmental origins of metabolic diseases
Almost 2 billion adults in the world are overweight, and more than half of them are classified
as obese, while nearly one-third of children globally experience poor growth and …
as obese, while nearly one-third of children globally experience poor growth and …
[HTML][HTML] Maternal–fetal nutrient transport in pregnancy pathologies: the role of the placenta
KE Brett, ZM Ferraro, J Yockell-Lelievre… - International journal of …, 2014 - mdpi.com
Appropriate in utero growth is essential for offspring development and is a critical contributor
to long-term health. Fetal growth is largely dictated by the availability of nutrients in maternal …
to long-term health. Fetal growth is largely dictated by the availability of nutrients in maternal …
Regulation of nutrient transport across the placenta
Abnormal fetal growth, both growth restriction and overgrowth, is associated with perinatal
complications and an increased risk of metabolic and cardiovascular disease later in life …
complications and an increased risk of metabolic and cardiovascular disease later in life …
[HTML][HTML] Placental responses to changes in the maternal environment determine fetal growth
KG Dimasuay, P Boeuf, TL Powell… - Frontiers in physiology, 2016 - frontiersin.org
Placental responses to maternal perturbations are complex and remain poorly understood.
Altered maternal environment during pregnancy such as hypoxia, stress, obesity, diabetes …
Altered maternal environment during pregnancy such as hypoxia, stress, obesity, diabetes …
Lipid metabolism during pregnancy and its implications for fetal growth
E Herrera, H Ortega-Senovilla - Current pharmaceutical …, 2014 - ingentaconnect.com
More glucose crosses the placenta than any other substrate, but correlations between its
concentration in maternal plasma and fetal growth are not found consistently. The …
concentration in maternal plasma and fetal growth are not found consistently. The …
Endocrine regulation of human fetal growth: the role of the mother, placenta, and fetus
VE Murphy, R Smith, WB Giles, VL Clifton - Endocrine reviews, 2006 - academic.oup.com
The environment in which the fetus develops is critical for its survival and long-term health.
The regulation of normal human fetal growth involves many multidirectional interactions …
The regulation of normal human fetal growth involves many multidirectional interactions …
Role of the placenta in fetal programming: underlying mechanisms and potential interventional approaches
Adverse influences during fetal life alter the structure and function of distinct cells, organ
systems or homoeostatic pathways, thereby 'programming'the individual for an increased …
systems or homoeostatic pathways, thereby 'programming'the individual for an increased …
[HTML][HTML] Maternal and fetal lipid metabolism under normal and gestational diabetic conditions
E Herrera, G Desoye - Hormone molecular biology and clinical …, 2016 - degruyter.com
Maternal lipids are strong determinants of fetal fat mass. Here we review the overall lipid
metabolism in normal and gestational diabetes mellitus (GDM) pregnancies. During early …
metabolism in normal and gestational diabetes mellitus (GDM) pregnancies. During early …
Maternal undernutrition influences placental-fetal development
L Belkacemi, DM Nelson, M Desai… - Biology of …, 2010 - academic.oup.com
Maternal nutrition during pregnancy has a pivotal role in the regulation of placental-fetal
development and thereby affects the lifelong health and productivity of offspring. Suboptimal …
development and thereby affects the lifelong health and productivity of offspring. Suboptimal …
[HTML][HTML] Oocyte maturation and quality: role of cyclic nucleotides
The developing fetus requires substantial amounts of fatty acids to support rapid cellular
growth and activity. Although the fatty acid composition delivered to the fetus is largely …
growth and activity. Although the fatty acid composition delivered to the fetus is largely …