[PDF][PDF] SARS-CoV-2 human T cell epitopes: Adaptive immune response against COVID-19
Over the past year, numerous studies in the peer reviewed and preprint literature have
reported on the virological, epidemiological and clinical characteristics of the coronavirus …
reported on the virological, epidemiological and clinical characteristics of the coronavirus …
Fundamentals and methods for T‐and B‐cell epitope prediction
JL Sanchez-Trincado… - Journal of …, 2017 - Wiley Online Library
Adaptive immunity is mediated by T‐and B‐cells, which are immune cells capable of
developing pathogen‐specific memory that confers immunological protection. Memory and …
developing pathogen‐specific memory that confers immunological protection. Memory and …
[PDF][PDF] Comprehensive analysis of T cell immunodominance and immunoprevalence of SARS-CoV-2 epitopes in COVID-19 cases
T cells are involved in control of SARS-CoV-2 infection. To establish the patterns of
immunodominance of different SARS-CoV-2 antigens and precisely measure virus-specific …
immunodominance of different SARS-CoV-2 antigens and precisely measure virus-specific …
Selective and cross-reactive SARS-CoV-2 T cell epitopes in unexposed humans
Many unknowns exist about human immune responses to the severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) virus. SARS-CoV-2–reactive CD4+ T cells have …
syndrome coronavirus 2 (SARS-CoV-2) virus. SARS-CoV-2–reactive CD4+ T cells have …
[PDF][PDF] Targets of T cell responses to SARS-CoV-2 coronavirus in humans with COVID-19 disease and unexposed individuals
Understanding adaptive immunity to SARS-CoV-2 is important for vaccine development,
interpreting coronavirus disease 2019 (COVID-19) pathogenesis, and calibration of …
interpreting coronavirus disease 2019 (COVID-19) pathogenesis, and calibration of …
[HTML][HTML] COVID-19 coronavirus vaccine design using reverse vaccinology and machine learning
To ultimately combat the emerging COVID-19 pandemic, it is desired to develop an effective
and safe vaccine against this highly contagious disease caused by the SARS-CoV-2 …
and safe vaccine against this highly contagious disease caused by the SARS-CoV-2 …
Optimization of therapeutic antibodies by predicting antigen specificity from antibody sequence via deep learning
The optimization of therapeutic antibodies is time-intensive and resource-demanding,
largely because of the low-throughput screening of full-length antibodies (approximately 1× …
largely because of the low-throughput screening of full-length antibodies (approximately 1× …
T cells from patients with Parkinson's disease recognize α-synuclein peptides
Genetic studies have shown the association of Parkinson's disease with alleles of the major
histocompatibility complex,,. Here we show that a defined set of peptides that are derived …
histocompatibility complex,,. Here we show that a defined set of peptides that are derived …
Linking neuroinflammation and neurodegeneration in Parkinson's disease
G Gelders, V Baekelandt… - Journal of immunology …, 2018 - Wiley Online Library
Neurodegenerative diseases such as Parkinson's disease (PD) and Alzheimer's disease
(AD) impose a pressing burden on our developed and consequently aging society …
(AD) impose a pressing burden on our developed and consequently aging society …
[HTML][HTML] The immune epitope database and analysis resource in epitope discovery and synthetic vaccine design
The task of epitope discovery and vaccine design is increasingly reliant on bioinformatics
analytic tools and access to depositories of curated data relevant to immune reactions and …
analytic tools and access to depositories of curated data relevant to immune reactions and …