Right ventricular (RV) function is the primary prognostic factor for both morbidity and
mortality in pulmonary hypertension (PH). RV hypertrophy is initially an adaptive …

Right-sided heart failure (RHF) occurs from impaired contractility of the right ventricle (RV)
caused by pressure, volume overload, or intrinsic myocardial contractile dysfunction leading …

The function of the right ventricle (RV) determines the prognosis of patients with pulmonary
hypertension. While much progress has been made in the treatment of pulmonary …

Background Therapy guided by pulmonary artery (PA) pressure monitoring reduces PA
pressures and heart failure hospitalizations (HFH) during the first year, but the durability of …

Pulmonary arterial hypertension (PAH) is a rare but lethal disorder caused by several
pathological changes in the pulmonary vasculature. There is endothelial cell dysfunction …

Background Impaired right ventricular (RV) pulmonary artery coupling has been associated
with higher mortality in patients with chronic heart disease, but few studies have examined …

The use of human induced pluripotent stem cell-derived cardiomyocytes (iPSC-CMs) as an
in vitro model of the heart is limited by their structurally and functionally immature …

Objectives To determine the prognostic value of patterns of right ventricular adaptation in
patients with pulmonary arterial hypertension (PAH), assessed using cardiac magnetic …

Pulmonary arterial hypertension (PAH) is characterized by pulmonary vascular remodeling.
Recent evidence supports that inflammation plays a key role in triggering and maintaining …

Background Qualitative and quantitative flow hemodynamic indexes have been shown to
reflect right ventricular (RV) afterload and function in pulmonary hypertension (PH). We …