[HTML][HTML] Advances of microfluidic lung chips for assessing atmospheric pollutants exposure
Atmospheric pollutants, including particulate matters, nanoparticles, bioaerosols, and some
chemicals, have posed serious threats to the environment and the human's health. The …
chemicals, have posed serious threats to the environment and the human's health. The …
Post-COVID Syndrome: The Research Progress in the Treatment of Pulmonary sequelae after COVID-19 Infection
V Ruggiero, RP Aquino, P Del Gaudio, P Campiglia… - Pharmaceutics, 2022 - mdpi.com
Post-COVID syndrome or long COVID is defined as the persistence of symptoms after
confirmed SARS-CoV-2 infection, the pathogen responsible for coronavirus disease. The …
confirmed SARS-CoV-2 infection, the pathogen responsible for coronavirus disease. The …
Differential interferon-α subtype induced immune signatures are associated with suppression of SARS-CoV-2 infection
J Schuhenn, TL Meister, D Todt… - Proceedings of the …, 2022 - National Acad Sciences
Type I interferons (IFN-I) exert pleiotropic biological effects during viral infections, balancing
virus control versus immune-mediated pathologies, and have been successfully employed …
virus control versus immune-mediated pathologies, and have been successfully employed …
Inhibition of SARS-CoV-2 replication in the lung with siRNA/VIPER polyplexes
SARS-CoV-2 has been the cause of a global pandemic since 2019 and remains a medical
urgency. siRNA-based therapies are a promising strategy to fight viral infections. By …
urgency. siRNA-based therapies are a promising strategy to fight viral infections. By …
Inhibition of Toll-like receptor 4 and Interleukin-1 receptor prevent SARS-CoV-2 mediated kidney injury
D Nakazawa, Y Takeda, M Kanda, U Tomaru… - Cell Death …, 2023 - nature.com
Acute kidney injury (AKI) is a common and severe complication of the coronavirus disease
2019 (COVID-19). Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) directly …
2019 (COVID-19). Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) directly …
Intracellular life cycle kinetics of SARS-CoV-2 predicted using mathematical modelling
D Grebennikov, E Kholodareva, I Sazonov… - Viruses, 2021 - mdpi.com
SARS-CoV-2 infection represents a global threat to human health. Various approaches were
employed to reveal the pathogenetic mechanisms of COVID-19. Mathematical and …
employed to reveal the pathogenetic mechanisms of COVID-19. Mathematical and …
Influenza viruses and coronaviruses: Knowns, unknowns, and common research challenges
The development of safe and effective vaccines in a record time after the emergence of the
Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) is a remarkable …
Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) is a remarkable …
Particle safety assessment in additive manufacturing: From exposure risks to advanced toxicology testing
Additive manufacturing (AM) or industrial three-dimensional (3D) printing drives a new
spectrum of design and production possibilities; pushing the boundaries both in the …
spectrum of design and production possibilities; pushing the boundaries both in the …
Pan-antiviral effects of a PIKfyve inhibitor on respiratory virus infection in human nasal epithelium and mice
J Baker, H Ombredane, L Daly, I Knowles… - Antimicrobial Agents …, 2024 - Am Soc Microbiol
Endocytosis, or internalization through endosomes, is a major cell entry mechanism used by
respiratory viruses. Phosphoinositide 5-kinase (PIKfyve) is a critical enzyme for the synthesis …
respiratory viruses. Phosphoinositide 5-kinase (PIKfyve) is a critical enzyme for the synthesis …
Human Nasal Epithelial Cells Sustain Persistent SARS-CoV-2 Infection In Vitro, despite Eliciting a Prolonged Antiviral Response
The dynamics of SARS-CoV-2 infection in COVID-19 patients are highly variable, with a
subset of patients demonstrating prolonged virus shedding, which poses a significant …
subset of patients demonstrating prolonged virus shedding, which poses a significant …