Recent progress on health effects and biosynthesis of two key sialylated human milk oligosaccharides, 3′-sialyllactose and 6′-sialyllactose

Y Zhu, J Zhang, W Zhang, W Mu - Biotechnology Advances, 2023 - Elsevier
Human milk oligosaccharides (HMOs), the third major solid component in breast milk, are
recognized as the first prebiotics for health benefits in infants. Sialylated HMOs are an …

Multifunctional benefits of prevalent HMOs: Implications for infant health

DR Hill, JM Chow, RH Buck - Nutrients, 2021 - mdpi.com
Breastfeeding is the best source of nutrition during infancy and is associated with a broad
range of health benefits. However, there remains a significant and persistent need for …

Recent understanding of human milk oligosaccharides in establishing infant gut microbiome and roles in immune system

RP Singh, J Niharika, KK Kondepudi, M Bishnoi… - Food Research …, 2022 - Elsevier
Human milk oligosaccharides (HMOs) are complex sugars with distinctive structural diversity
present in breast milk. HMOs have various functional roles to play in infant development …

Human milk oligosaccharides as bioactive compounds in infant formula: recent advances and trends in synthetic methods

E Pérez-Escalante, S Alatorre-Santamaría… - Critical Reviews in …, 2022 - Taylor & Francis
Human milk oligosaccharides (HMO) have attracted great interest in recent years due to
their role in boosting infants and adults health. According to several in vitro, in vivo and …

The intriguing roles of Siglec family members in the tumor microenvironment

KY Jiang, LL Qi, FB Kang, L Wang - Biomarker Research, 2022 - Springer
Sialic acid-binding receptors are expressed on the surfaces of a variety of immune cells and
have complex and diverse immunoregulatory functions in health and diseases. Recent …

Current perspective of sialylated milk oligosaccharides in mammalian milk: implications for brain and gut health of newborns

M Hobbs, M Jahan, SA Ghorashi, B Wang - Foods, 2021 - mdpi.com
Human milk oligosaccharides (HMOs) are the third most abundant solid component after
lactose and lipids of breast milk. All mammal milk contains soluble oligosaccharides …

Current advances in structure–function relationships and dose-dependent effects of human milk oligosaccharides

J Wang, MS Chen, RS Wang, JQ Hu, S Liu… - Journal of Agricultural …, 2022 - ACS Publications
HMOs (human milk oligosaccharides) are the third most important nutrient in breast milk. As
complex glycans, HMOs play an important role in regulating neonatal intestinal immunity …

Systemic lectin-glycan interaction of pathogenic enteric bacteria in the gastrointestinal tract

SH Cho, J Park, CH Kim - International Journal of Molecular Sciences, 2022 - mdpi.com
Microorganisms, such as bacteria, viruses, and fungi, and host cells, such as plants and
animals, have carbohydrate chains and lectins that reciprocally recognize one another. In …

Potential biological functions and future perspectives of sialylated milk oligosaccharides

TLL Nguyen, DV Nguyen, KS Heo - Archives of Pharmacal Research, 2024 - Springer
Sialyllactoses (SLs) primarily include sialylated human milk oligosaccharides (HMOs) and
bovine milk oligosaccharides (BMOs). First, the safety assessment of 3′-sialyllactose (3 …

[HTML][HTML] Comparison of different labeling techniques for the LC-MS profiling of human milk oligosaccharides

Y Lang, Y Zhang, C Wang, L Huang, X Liu… - Frontiers in …, 2021 - frontiersin.org
Human milk oligosaccharides (HMOs) exhibit various biological activities for infants, such as
serving as prebiotics, blocking pathogens, and aiding in brain development. HMOs are a …