Antiinflammatory potential of medicinal plants: A source for therapeutic secondary metabolites

N Bernstein, M Akram, M Daniyal, H Koltai… - Advances in …, 2018 - Elsevier
Plants containing natural products have been used worldwide in traditional medicine since
antiquity and are a source of potential and powerful drugs. The potential of higher plants as …

Improved insulin sensitivity in obese-diabetic mice via chitosan Nanomicelles mediated silencing of pro-inflammatory Adipocytokines

D Sharma, S Arora, A Banerjee, J Singh - … : Nanotechnology, Biology and …, 2021 - Elsevier
Obesity induced chronic low-level inflammation is strongly associated with the development
of insulin resistance and progression of type-2 diabetes. Systemic treatment with anti …

[HTML][HTML] The role of immune mechanisms in abdominal aortic aneurysm: could it be a promising therapeutic strategy?

R Dinc - Acta Cardiologica Sinica, 2023 - ncbi.nlm.nih.gov
Abdominal aortic aneurysm (AAA) is an enlargement of the aorta greater than 50% in
diameter. Although up to 80% of cases result in mortality if the aneurysm ruptures, patients …

The role, involvement and function (s) of interleukin-35 and interleukin-37 in disease pathogenesis

R Omenesa Bello, VK Chin… - International Journal of …, 2018 - mdpi.com
The recently identified cytokines—interleukin (IL)-35 and interleukin (IL)-37—have been
described for their anti-inflammatory and immune-modulating actions in numerous …

Immunomodulatory effects of fish peptides on cardiometabolic syndrome associated risk factors: A review

S Abachi, G Pilon, A Marette, L Bazinet… - Food Reviews …, 2023 - Taylor & Francis
Many types of marine-derived products specifically biopeptides, among other health
benefiting properties, such as anti-oxidation, anti-infection, anti-hypertension, can also …

Clinical translation of immunomodulatory therapeutics

A Nash, S Aghlara-Fotovat, A Hernandez… - Advanced drug delivery …, 2021 - Elsevier
Immunomodulatory therapeutics represent a unique class of drug products that have
tremendous potential to rebalance malfunctioning immune systems and are quickly …

Anti-IL-10 antibody humanization by SDR grafting with enhanced affinity to neutralize the adverse response of interleukin-10

P Chouhan, S Singh, V Sharma… - International Journal of …, 2022 - Springer
The overexpression of IL-10 is associated with numerous diseases like lymphoma,
melanoma, systemic lupus erythematosus, systemic sclerosis, and bullous diseases. To …

Ferulic acid supplementation for management of depression in epilepsy

T Singh, T Kaur, RK Goel - Neurochemical Research, 2017 - Springer
Neuroinflammation driven altered neurochemical milieu have been reported to play a
significant role in pathogenesis of comorbid depression in epilepsy. Most of the antiepileptic …

Discovering in vivo cytokine-eQTL interactions from a lupus clinical trial

EE Davenport, T Amariuta, M Gutierrez-Arcelus… - Genome biology, 2018 - Springer
Background Cytokines are critical to human disease and are attractive therapeutic targets
given their widespread influence on gene regulation and transcription. Defining the …

[HTML][HTML] In silico prediction of phytoconstituents from Ehretia laevis targeting TNF-α in arthritis

SR Yende, SK Shah, SK Arora, KS Moharir… - Digital Chinese …, 2021 - Elsevier
Objective Rheumatoid arthritis (RA) is an autoimmune disease involving the synovial lining
of the major joints. Current therapies have noteworthy side effects. Our study involved in …